Department of Internal Medicine, Centre Hospitalier, 179 boulevard Marechal Juin, 26953, Valence Cedex 9, France.
Rheumatol Int. 2013 Sep;33(9):2411-5. doi: 10.1007/s00296-012-2412-6. Epub 2012 Mar 28.
Camptocormia, an abnormal truncal flexion posture that occurs while walking or standing, is usually caused by various hypokinetic movement disorders, mainly Parkinson disease. We describe the case of a man with subacute onset of camptocormia. Quadriceps muscle biopsy showed significant rhabdomyolysis, few isolated inflammatory cells and mild expression of type I MHC in few fibers, a pattern usually found in immune-mediated necrotizing myopathies. Myositis was associated with Raynaud's phenomenon, mild sclerodactyly, and anti-Ku antibodies leading to the diagnosis of polymyositis/systemic sclerosis overlap myositis. The posture showed modest improvement in response to treatment.
驼背，一种在行走或站立时发生的异常躯干弯曲姿势，通常由各种运动障碍引起，主要是帕金森病。我们描述了一例亚急性起病的驼背患者。股四头肌活检显示明显的横纹肌溶解，少数孤立的炎症细胞和少数纤维中轻度表达 I 型 MHC，这种模式通常见于免疫介导的坏死性肌病。肌炎伴有雷诺现象、轻度硬皮病和抗 Ku 抗体，导致重叠性多发性肌炎/系统性硬化症的诊断。该姿势在治疗后有一定程度的改善。
