硬皮病-多发性肌炎重叠综合征伴抗Ku抗体及镶边空泡形成
Scleroderma-polymyositis overlap syndrome associated with anti-Ku antibody and rimmed vacuole formation.
作者信息
Yamanishi Y, Maeda H, Katayama S, Ishioka S, Yamakido M
机构信息
Second Department of Internal Medicine, Hiroshima University School of Medicine, Japan.
出版信息
J Rheumatol. 1996 Nov;23(11):1991-4.
PMID:8923381
Abstract
Scleroderma-polymyositis overlap syndrome is strongly associated with certain autoantibodies, such as anti-PM-Scl antibody and anti-Ku antibody. We describe a case of scleroderma-polymyositis overlap syndrome associated with anti-Ku antibody, which revealed rimmed vacuole formation in addition to intranuclear and intracytoplasmic filamentous inclusions in muscle biopsy specimens.
摘要
硬皮病-多发性肌炎重叠综合征与某些自身抗体密切相关，如抗PM-Scl抗体和抗Ku抗体。我们描述了一例与抗Ku抗体相关的硬皮病-多发性肌炎重叠综合征病例，该病例在肌肉活检标本中除了有核内和胞浆内丝状包涵体外，还显示有镶边空泡形成。
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