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胚胎期暴露于雄激素和他莫昔芬后肉鸡肥胖对睾酮的反应。

The response of broilers' adiposity to testosterone after embryonic exposure to androgen and tamoxifen.

作者信息

Rozenboim I, Robinzon B, Ron B, Arnon E, Snapir N

机构信息

Department of Animal Science, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel.

出版信息

Br Poult Sci. 1990 Sep;31(3):645-50. doi: 10.1080/00071669008417295.

DOI:10.1080/00071669008417295
PMID:2245356
Abstract
  1. The effects of early exposure of heavy breed (HB) chicks to an anti-oestrogen (tamoxifen--TAM) and to an androgen which cannot be aromatised (5 alpha-dihydrotestosterone--DHT) on subsequent adiposity and its response to testosterone were studied. 2. Embryonic TAM administration reduced adiposity in females but not in males at 8 weeks of age. Embryonic DHT produced similar responses but to a lesser extent. 3. Testosterone propionate (TP) administration during growth had no effect on adiposity in any of the treated groups but TP reduced adiposity in males which had been exposed to DHT at the embryonic stage.
摘要
  1. 研究了重体型(HB)雏鸡早期接触抗雌激素(他莫昔芬 - TAM)和一种不能芳香化的雄激素(5α - 双氢睾酮 - DHT)对随后肥胖及其对睾酮反应的影响。2. 胚胎期给予TAM可降低8周龄雌性雏鸡的肥胖程度,但对雄性雏鸡无此作用。胚胎期给予DHT产生了类似的反应,但程度较轻。3. 生长期间给予丙酸睾酮(TP)对任何处理组的肥胖程度均无影响,但TP可降低胚胎期接触过DHT的雄性雏鸡的肥胖程度。

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The response of broilers' adiposity to testosterone after embryonic exposure to androgen and tamoxifen.胚胎期暴露于雄激素和他莫昔芬后肉鸡肥胖对睾酮的反应。
Br Poult Sci. 1990 Sep;31(3):645-50. doi: 10.1080/00071669008417295.
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Effect of embryonic and neonatal administration of tamoxifen on adiposity in the broiler chicken.胚胎期和新生期给予他莫昔芬对肉鸡肥胖的影响。
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