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胚胎期和新生期给予他莫昔芬对肉鸡肥胖的影响。

Effect of embryonic and neonatal administration of tamoxifen on adiposity in the broiler chicken.

作者信息

Rozenboim I, Robinzon B, Arnon E, Snapir N

机构信息

Department of Animal Science, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel.

出版信息

Br Poult Sci. 1989 Sep;30(3):607-12. doi: 10.1080/00071668908417183.

DOI:10.1080/00071668908417183
PMID:2819503
Abstract
  1. The effect of early exposure of heavy breed (HB) chicks to an anti-oestrogen (tamoxifen--TAM) on later adiposity was studied. 2. TAM administration at the embryonic stage, but not at the day of hatching, reduced adiposity in females but not in males, at 8 to 9 weeks of age. This reduction in adiposity in females minimised or even alleviated the excess of fat in females compared to males.
摘要
  1. 研究了重型品种(HB)雏鸡早期接触抗雌激素(他莫昔芬 - TAM)对后期肥胖的影响。2. 在胚胎期而非孵化当天给予他莫昔芬,可降低8至9周龄雌性雏鸡的肥胖程度,但对雄性雏鸡无效。与雄性相比,雌性雏鸡肥胖程度的降低使雌性体内过多的脂肪量降至最低甚至减轻。

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