Parker-Autry Candace, Harvie Heidi, Arya Lily A, Northington Gina M
From the *Division of Women's Pelvic Medicine and Reconstructive Surgery,Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL; †Chestnut Hill Women's Health Associates; and ‡Division of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynecology, University of Pennsylvania School ofMedicine, Philadelphia, PA.
Female Pelvic Med Reconstr Surg. 2011 Mar;17(2):91-6. doi: 10.1097/SPV.0b013e31820c99a9.
: To examine the prevalence of lower urinary tract symptoms (LUTS) in women with symptomatic uterine fibroids and investigate their relationship with fibroid location and uterine volume.
: This was a cross-sectional study including 78 women seeking surgical treatment for symptomatic uterine fibroids. The validated Bristol Female Lower Urinary Tract Symptom-Scored Form (BFLUTS-SF) questionnaire was administered before surgical intervention. Uterine volume and BFLUTS-SF subscale scores or symptoms were compared using Student t test. Multivariate models explored the association between dominant fibroid location and BFLUTS-SF subscale scores.
: The most prevalent LUTS were nocturia (91%), urgency (59%), and urinary incontinence (45%-54%). Mean uterine volume and length were 672 ± 714 cm and 13 ± 4.24 cm, respectively. Women with moderate and severe urinary urgency had significantly larger uterine volumes (P = 0.017). Mean voiding subscale scores were significantly higher in women with dominant anterior fibroids compared with those with non-anterior fibroids (voiding subscale scores, 2.84 ± 3.03 vs 1.30 ± 2.07, respectively; P < 0.01). This remained significant after adjusting for age, parity, body mass index, and imaging modality.
: Lower urinary tract symptoms are prevalent in patients with symptomatic uterine fibroids. Further study is needed to determine if surgical therapy improves these LUTSs in this population.
研究有症状子宫肌瘤女性下尿路症状（LUTS）的患病率，并探讨其与肌瘤位置和子宫体积的关系。
这是一项横断面研究，纳入78例因有症状子宫肌瘤寻求手术治疗的女性。在手术干预前使用经过验证的布里斯托尔女性下尿路症状评分表（BFLUTS-SF）问卷。采用Student t检验比较子宫体积和BFLUTS-SF子量表评分或症状。多变量模型探讨主要肌瘤位置与BFLUTS-SF子量表评分之间的关联。
最常见的LUTS是夜尿症（91%）、尿急（59%）和尿失禁（45%-54%）。平均子宫体积和长度分别为672±714 cm和13±4.24 cm。中度和重度尿急的女性子宫体积明显更大（P = 0.017）。主要肌瘤位于前方的女性排尿子量表评分显著高于肌瘤不在前方的女性（排尿子量表评分分别为2.84±3.03和1.30±2.07；P < 0.01）。在调整年龄、产次、体重指数和成像方式后，这一差异仍然显著。
有症状子宫肌瘤患者中普遍存在下尿路症状。需要进一步研究以确定手术治疗是否能改善该人群的这些LUTS。
