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子宫肌瘤手术对下尿路症状的影响。

Impact of uterine fibroid surgery on lower urinary tract symptoms.

作者信息

Berujon Elsa, Thubert Thibault, Fauvet Raffaèle, Villot Anne, Pizzoferrato Anne-Cécile

机构信息

Department of Gynecology and Obstetrics, University Hospital Center of Caen Normandie, Caen, France.

Department of Gynecology and Obstetrics, University Hospital Center of Nantes, Nantes, France.

出版信息

J Gynecol Obstet Hum Reprod. 2022 May;51(5):102355. doi: 10.1016/j.jogoh.2022.102355. Epub 2022 Mar 13.

DOI:10.1016/j.jogoh.2022.102355
PMID:35296450
Abstract

OBJECTIVE

Uterine fibroids are often associated with lower urinary tract symptoms (LUTS), the exact prevalence of which has been underexplored. Our main objective was to evaluate the effect of surgical treatment of fibroids on LUTS. Our secondary objectives were to assess the prevalence of LUTS in women undergoing fibroid surgery and to analyze the relationship between the characteristics of fibroids and the severity of symptoms.

METHODS

This was a prospective study of women conducted between 2019 and 2021. The main endpoint was the change in the total UDI-6, IIQ7, ICIQ-SF and CONTILIFE scores preoperatively and 6 weeks postoperatively.

RESULTS

Of the 55 included women, 63.6% had frequency and 60% had urgency. Six weeks postoperatively, urinary symptoms had significantly improved for all scores. The presence of an anterior fibroid was significantly associated with higher urinary symptom scores for the UDI-6 (p = 0.007) and ICIQ-SF scores (p = 0.04). The size of the uterus or dominant fibroid was not significantly associated with the severity of urinary symptoms.

CONCLUSION

Fibroids are often associated with symptoms of overactive bladder. An anterior location of the fibroid appears to be associated with greater severity scores. Surgical treatment appears to reduce urinary symptoms 6 weeks postoperatively.

摘要

目的

子宫肌瘤常与下尿路症状(LUTS)相关,但其确切患病率尚未得到充分研究。我们的主要目的是评估子宫肌瘤手术治疗对LUTS的影响。次要目的是评估接受肌瘤手术的女性中LUTS的患病率,并分析肌瘤特征与症状严重程度之间的关系。

方法

这是一项对2019年至2021年间女性进行的前瞻性研究。主要终点是术前和术后6周时UDI-6、IIQ7、ICIQ-SF和CONTILIFE总分的变化。

结果

在纳入的55名女性中,63.6%有尿频症状,60%有尿急症状。术后6周,所有评分的尿路症状均有显著改善。前位肌瘤的存在与UDI-6(p = 0.007)和ICIQ-SF评分(p = 0.04)的较高尿路症状评分显著相关。子宫或主要肌瘤的大小与尿路症状的严重程度无显著相关性。

结论

子宫肌瘤常与膀胱过度活动症症状相关。肌瘤位于前方似乎与更高的严重程度评分相关。手术治疗似乎能在术后6周减轻尿路症状。

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Impact of uterine fibroid surgery on lower urinary tract symptoms.子宫肌瘤手术对下尿路症状的影响。
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Pre-operative GnRH analogue therapy before hysterectomy or myomectomy for uterine fibroids.子宫肌瘤患者在子宫切除术或肌瘤切除术之前进行术前促性腺激素释放激素类似物治疗。
Cochrane Database Syst Rev. 2000(2):CD000547. doi: 10.1002/14651858.CD000547.

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