Dancz Christina E, Kadam Priyanka, Li Carrie, Nagata Kristen, Özel Begüm
Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, 1200 N State St IRD 510, Los Angeles, CA, 90033, USA,
Int Urogynecol J. 2014 Feb;25(2):241-8. doi: 10.1007/s00192-013-2183-y. Epub 2013 Aug 7.
To compare pelvic floor symptoms in women with a leiomyomatous uterus ≤12 weeks and those >12 weeks in size and to evaluate the resolution of these symptoms after surgical intervention.
The PFDI-20, PFIQ-7 and 3-day voiding diaries were administered prospectively to all subjects. Demographics and questionnaire responses were compared using a t test, Chi-squared test or Mann-Whitney U test as indicated.
One hundred and forty-five women completed the questionnaires and were included for analysis. There were 58 women with uterine size ≤12 weeks (group I) and 87 women with size >12 weeks (group II). Participants in group I reported more straining to defecate (p = 0.042), while group II reported increased feeling of incomplete bladder emptying (p = 0.007) and difficulty emptying their bladder (p = 0.008). Review of ultrasound images revealed no difference in pelvic floor symptoms when stratified by leiomyoma location. At 1-year follow-up, 69 women (48 %) responded, and 40 (58 %) had undergone surgical intervention. Surgery was shown to improve symptoms for all questions reviewed at 1-year follow-up.
A leiomyomatous uterus >12 weeks is associated with the symptom of incomplete bladder emptying, but does not appear to have an effect on other pelvic floor symptoms compared with women with a smaller leiomyomatous uterus. Surgical intervention for leiomyomata improves pelvic floor symptoms.
比较子宫平滑肌瘤大小≤12周和>12周的女性的盆底症状,并评估手术干预后这些症状的缓解情况。
对所有受试者前瞻性地进行PFDI-20、PFIQ-7和3天排尿日记评估。根据需要使用t检验、卡方检验或曼-惠特尼U检验比较人口统计学和问卷回复情况。
145名女性完成问卷并纳入分析。子宫大小≤12周的女性有58名(I组),>12周的女性有87名(II组)。I组参与者报告排便时用力更多(p = 0.042),而II组报告膀胱排空不尽感增加(p = 0.007)及排尿困难(p = 0.008)。超声图像回顾显示,按平滑肌瘤位置分层时盆底症状无差异。在1年随访时,69名女性(48%)回复,40名(58%)接受了手术干预。1年随访时对所有评估问题而言,手术均显示可改善症状。
子宫平滑肌瘤>12周与膀胱排空不尽症状相关,但与较小子宫平滑肌瘤的女性相比,似乎对其他盆底症状无影响。平滑肌瘤的手术干预可改善盆底症状。