Great Ormond St Hospital - Paediatric Nephrology, Great Ormond Street, London, WC1N 3JH, UK.
Pediatr Nephrol. 2013 Feb;28(2):191-6. doi: 10.1007/s00467-012-2151-7. Epub 2012 Mar 28.
Renovascular hypertension (RVH) can be caused by many different diseases, with the most common being fibromuscular dysplasia (FMD) and Takayasu arteritis (TA). A strikingly different diagnostic pattern is seen in children with RVH from different parts of the world. In Europe and North America, these children are mainly diagnosed as having FMD while in Asia and South Africa they will most often get a diagnosis of TA. When comparing the clinical diagnosis for FMD and TA, it becomes obvious that there is a great deal of overlap between the definitions of these two conditions. Different ways to come to the most accurate diagnosis using imaging of the blood vessel wall and positron emission tomography (PET) will be discussed. How an accurate diagnosis should influence the treatment of the children with these conditions will also be addressed.
肾血管性高血压（RVH）可由多种不同疾病引起，最常见的是纤维肌性发育不良（FMD）和 Takayasu 动脉炎（TA）。来自世界不同地区的患有 RVH 的儿童的诊断模式明显不同。在欧洲和北美，这些儿童主要被诊断为 FMD，而在亚洲和南非，他们通常会被诊断为 TA。当比较 FMD 和 TA 的临床诊断时，很明显这两种疾病的定义有很大的重叠。将讨论使用血管壁成像和正电子发射断层扫描（PET）来获得最准确诊断的不同方法。准确的诊断应该如何影响这些疾病患儿的治疗也将得到解决。
