Lee Ki Wuk, Lee Sang Taek, Cho Heeyeon
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean J Pediatr. 2016 Nov;59(Suppl 1):S145-S148. doi: 10.3345/kjp.2016.59.11.S145. Epub 2016 Nov 30.
Takayasu arteritis (TA) is a chronic inflammatory disease of unknown etiology that affects mainly the aorta, main aortic branches, and pulmonary arteries. Diverse neurological manifestations of TA have rarely been reported in children. Posterior reversible encephalopathy syndrome (PRES) is a neuroradiological condition that presents with headache, seizure, visual disturbances, and characteristic lesions on imaging. Inflammatory condition and severe hypertension in TA can cause PRES. We report of a 5-year-old girl with presumed TA who presented with PRES and chronic total occlusion in the renal artery. The findings on magnetic resonance imaging suggested PRES. Left nephrectomy was performed for total occlusion of the left renal artery, and the confirmatory diagnosis of TA was based on the pathologic findings of the renal artery.
高安动脉炎（TA）是一种病因不明的慢性炎症性疾病，主要累及主动脉、主动脉主要分支和肺动脉。儿童TA的各种神经表现鲜有报道。后部可逆性脑病综合征（PRES）是一种神经放射学疾病，表现为头痛、癫痫发作、视觉障碍以及影像学上的特征性病变。TA中的炎症状态和严重高血压可导致PRES。我们报告了一名5岁疑似TA的女孩，她出现了PRES和肾动脉慢性完全闭塞。磁共振成像结果提示为PRES。因左肾动脉完全闭塞进行了左肾切除术，TA的确诊基于肾动脉的病理检查结果。
