Macias E A, Rana F, Blazyk J, Modrzakowski M C
Department of Zoological and Biomedical Sciences, College of Osteopathic Medicine, Ohio University, Athens 45701.
Can J Microbiol. 1990 Aug;36(8):582-4. doi: 10.1139/m90-102.
Salmonella typhimurium and a series of rough lipopolysaccharide mutants derived from it were used as target bacteria to examine the antimicrobial capacity of magainin 2. Magainin 2 demonstrated a dose-related bactericidal activity against the smooth parent strain and the series of lipopolysaccharide mutants. The lipopolysaccharide mutant series showed an ordered increase in sensitivity to the magainin 2 as the depth of the rough lesion in the lipopolysaccharide increased.
鼠伤寒沙门氏菌及其衍生的一系列粗糙型脂多糖突变体被用作靶细菌，以检测马盖宁2的抗菌能力。马盖宁2对光滑型亲本菌株和一系列脂多糖突变体表现出剂量相关的杀菌活性。随着脂多糖中粗糙病变深度的增加，脂多糖突变体系列对马盖宁2的敏感性呈有序增加。
