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Clin Orthop Relat Res. 2013 Apr;471(4):1186-90. doi: 10.1007/s11999-012-2324-5.
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本文引用的文献

1
A missense mutation in the aggrecan C-type lectin domain disrupts extracellular matrix interactions and causes dominant familial osteochondritis dissecans.一种聚集蛋白聚糖 C 型凝集素结构域的错义突变破坏细胞外基质相互作用,并导致显性家族性剥脱性骨软骨炎。
Am J Hum Genet. 2010 Feb 12;86(2):126-37. doi: 10.1016/j.ajhg.2009.12.018. Epub 2010 Feb 4.
2
Bilateral osteochondritis dissecans of the knees in monozygotic twins: the genetic factor and review of the etiology.单卵双胞胎双侧膝关节剥脱性骨软骨炎:遗传因素及病因学综述
Am J Orthop (Belle Mead NJ). 2009 Sep;38(9):E152-5.
3
Osteochondritis dissecans of the glenoid: a rare injury secondary to repetitive microtrauma.肩胛盂剥脱性骨软骨炎:一种因反复微小创伤继发的罕见损伤。
J Trauma. 2009 Sep;67(3):E62-4. doi: 10.1097/TA.0b013e318047c02a.
4
Case report: Osteochondritis dissecans in twins: treatment with fresh osteochondral grafts.病例报告:双胞胎的剥脱性骨软骨炎:采用新鲜的骨软骨移植物治疗。
Clin Orthop Relat Res. 2010 Mar;468(3):893-7. doi: 10.1007/s11999-009-1017-1. Epub 2009 Aug 7.
5
Bicondylar osteochondritis dissecans in the knee: a report of two cases.膝关节双髁剥脱性骨软骨炎:两例报告
J Bone Joint Surg Br. 2008 Feb;90(2):232-5. doi: 10.1302/0301-620X.90B2.19705.
6
Osteochondritis dissecans of the knee.膝关节剥脱性骨软骨炎
J Am Acad Orthop Surg. 2006 Feb;14(2):90-100. doi: 10.5435/00124635-200602000-00004.
7
Relationship between osteochondritis dissecans of the lateral femoral condyle and lateral menisci types.股骨外侧髁剥脱性骨软骨炎与外侧半月板类型之间的关系。
J Pediatr Orthop. 2006 Jan-Feb;26(1):79-82. doi: 10.1097/01.bpo.0000191554.34197.fd.
8
Familial osteochondritis dissecans.家族性剥脱性骨软骨炎
J Bone Joint Surg Br. 1955 Feb;37-B(1):142-5. doi: 10.1302/0301-620X.37B1.142.
9
Osteochondritis dissecans of the knee in children.儿童膝关节剥脱性骨软骨炎
Curr Opin Pediatr. 2003 Feb;15(1):38-44. doi: 10.1097/00008480-200302000-00007.
10
Osteochondritis Dissecans of the Knee: Treatment of Juvenile and Adult Forms.膝关节剥脱性骨软骨炎:青少年及成人型的治疗
J Am Acad Orthop Surg. 1995 Jul;3(4):237-247. doi: 10.5435/00124635-199507000-00006.

一个膝关节内有三个剥脱性骨软骨炎病灶:病例报告。

Three osteochondritis dissecans lesions in one knee: a case report.

机构信息

Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City, UT, USA.

出版信息

Clin Orthop Relat Res. 2013 Apr;471(4):1186-90. doi: 10.1007/s11999-012-2324-5.

DOI:10.1007/s11999-012-2324-5
PMID:22453935
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3586005/
Abstract

BACKGROUND

Osteochondritis dissecans (OCD) has been defined as a localized process in which a focus of subchondral bone and adjacent articular cartilage separates from the surrounding bone. With the knee being the most common location for OCD development and the propensity for this lesion to be found in those who participate in sports, a repetitive microtrauma hypothesis for its cause has gained favor. However, the cause of OCD remains controversial, as does the most appropriate treatment for the varying degrees of OCD lesions.

CASE DESCRIPTION

We present a unique case of three OCD lesions in one knee. The patient was a young, athletic boy who developed three separate OCD lesions in his right knee over the course of 4 years. Temporally, the OCD lesions developed first in the lateral femoral condyle, then in the medial femoral condyle, and finally in the trochlea.

LITERATURE REVIEW

Our literature review yielded a few reports of bicondylar OCD lesions. We identified no previous reports of three separate OCD lesions found in a single joint.

PURPOSES AND CLINICAL RELEVANCE

This report illustrates how a uniquely affected knee with three OCD lesions was treated in three different ways with resolution of symptoms. Each of the OCD lesions was evaluated individually and treatment for each based on the severity of the lesion from the physical examination, imaging studies, and arthroscopic findings.

摘要

背景

剥脱性骨软骨炎(OCD)被定义为一种局限性病变,其中一个骨软骨下骨和相邻关节软骨的焦点与周围骨骼分离。由于膝关节是 OCD 发展最常见的部位,并且这种病变容易发生在参与运动的人群中,因此重复性微创伤假说已被广泛接受。然而,OCD 的病因仍存在争议,其各种程度的 OCD 病变的最佳治疗方法也存在争议。

病例描述

我们报告了一个独特的膝关节内三个 OCD 病变的病例。该患者是一位年轻的运动员男孩,在 4 年内右膝关节先后出现了三个独立的 OCD 病变。从时间上看,OCD 病变首先出现在外侧股骨髁,然后出现在内侧股骨髁,最后出现在滑车。

文献综述

我们的文献复习仅发现少数关于双髁 OCD 病变的报告。我们没有发现以前有报告指出在单个关节内发现三个独立的 OCD 病变。

目的和临床意义

本报告说明了如何以三种不同的方式治疗一个独特受累的膝关节,该膝关节有三个 OCD 病变,症状得到缓解。每个 OCD 病变都单独进行评估,并根据体格检查、影像学研究和关节镜检查结果,根据病变的严重程度进行治疗。