Department of Chemistry, Jinan University, Guangzhou 510632, PR China.
Chem Asian J. 2012 Jun;7(7):1664-70. doi: 10.1002/asia.201200045. Epub 2012 Mar 27.
Silver nanoparticles (AgNPs) are increasingly used in daily life for their antibacterial properties, but their low stability and high cytotoxicity hamper practical applications. In this work, sodium 1-naphthalenesulfonate-functionalized reduced graphene oxide (NA-rGO) was used as a substrate for AgNPs to produce a AgNP-NA-rGO hybrid. This hybrid showed substantially higher antibacterial activity than polyvinyl pyrrolidone (PVP)-stabilized AgNPs, and the AgNPs on NA-rGO were more stable than the AgNPs on PVP, resulting in long-term antibacterial effects. More importantly, this hybrid showed excellent water solubility and low cytotoxicity, suggesting the great potential application as sprayable reduced graphene oxide based antibacterial solutions.
银纳米粒子（AgNPs）因其抗菌性能而在日常生活中得到越来越多的应用，但它们的低稳定性和高细胞毒性阻碍了实际应用。在这项工作中，我们使用 1-萘磺酸钠功能化还原氧化石墨烯（NA-rGO）作为 AgNPs 的基底来制备 AgNP-NA-rGO 杂化材料。与聚乙烯吡咯烷酮（PVP）稳定的 AgNPs 相比，该杂化材料显示出更高的抗菌活性，而且 AgNPs 在 NA-rGO 上比在 PVP 上更稳定，从而产生长期的抗菌效果。更重要的是，该杂化材料具有优异的水溶性和低细胞毒性，表明其作为可喷涂基于还原氧化石墨烯的抗菌溶液具有巨大的应用潜力。
