化学分析及研究染料木藤（Maclura tinctoria （L.）D. Don ex Steud.）的木材和树皮中的酚类物质、抗氧化活性和抗菌作用。
Chemical Analysis and Study of Phenolics, Antioxidant Activity, and Antibacterial Effect of the Wood and Bark of Maclura tinctoria (L.) D. Don ex Steud.
机构信息
Instituto de Química, Universidade Federal de Uberlândia, Avenida João Naves de Ávila 2121, 38400-902 Uberlândia, MG, Brazil.
出版信息
Evid Based Complement Alternat Med. 2012;2012:451039. doi: 10.1155/2012/451039. Epub 2012 Feb 19.
Maclura tinctoria (L.) D. Don ex Steud. has one of the highest qualities among the coefficients for Brazilian woods (up to 9.6) and resistance rates equivalent to Indian teak (Tectona grandis). In this study, the macromolecular constituents and total phenols compounds as well as the antioxidant and antibacterial activities of this wood were evaluated. Total phenols and proanthocyanidin levels were higher in wood when compared with bark levels. The antioxidant activity of wood extracts (IC(50) = 18.7 μg/mL) was more effective than that of bark extracts (IC(50) = 20.9 μg/mL). Wood and bark extracts revealed a high potential for inhibition of aerobic and anaerobic bacteria. The bark extracts were the most active (MIC from 20 to 60 μg/mL). Both antioxidant activity and high potential for bacteria inhibition turn these extracts promising for drug formulations, especially as antibacterial agent.
蓬蘽（Maclura tinctoria (L.) D. Don ex Steud.）的木材系数在巴西木材中名列前茅（高达 9.6），且其抗阻力率与印度紫檀（Tectona grandis）相当。本研究评估了这种木材的高分子成分和总酚类化合物，以及其抗氧化和抗菌活性。与树皮相比，木材中的总酚类化合物和原花青素含量更高。木材提取物的抗氧化活性（IC50 = 18.7μg/mL）优于树皮提取物（IC50 = 20.9μg/mL）。木材和树皮提取物对需氧菌和厌氧菌均具有高抑制潜力。树皮提取物的活性最强（MIC 为 20 至 60μg/mL）。抗氧化活性和高抑菌潜力使这些提取物有望用于药物制剂，特别是作为抗菌剂。
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