奥沙米特，一种新型口服活性药物，它既能抑制过敏介质的释放，又能抑制其作用。
Oxatomide, a new orally active drug which inhibits both the release and the effects of allergic mediators.
作者信息
Awouters F, Niemegeers C J, Van den Berk J, Van Neuten J M, Lenaerts F M, Borgers M, Schellekens K H, Broeckaert A, De Cree J, Janssen P A
出版信息
Experientia. 1977 Dec 15;33(12):1657-9. doi: 10.1007/BF01934056.
Oxatomide is a new potent inhibitor of anaphylactic and allergic reactions. After oral administration, the compound both inhibits the release of endogenous histamine and prevents the effects of exogensous histamine, at comparable doses. The combination of these effects appears to be the basis of the effectiveness of oxatomide in allergic reactions and may lead to clinical application different from classical antihistaminics and from cromoglycate.
奥沙米特是一种新型强效的过敏反应抑制剂。口服给药后，该化合物在相当剂量下既能抑制内源性组胺的释放，又能阻止外源性组胺的作用。这些作用的联合似乎是奥沙米特在过敏反应中发挥疗效的基础，并且可能导致其临床应用不同于传统抗组胺药和色甘酸盐。
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