[The trends and progress in the comprehensive treatments of urological malignance].

Urological malignance include a group of cancers of urinary system, the incidence of urological cancer shows increasing trend, while the increasing progress in both surgical and non-surgical treatments leads to better therapeutic effects to the patients of urological oncology. For example, more and more prostatic cancers are promptly diagnosed in the stage of organ-confined disease which is suitable for curable therapies, and the surgical technique of radical prostatectomy is well established and being optimized to guarantee the outcome of prostate cancer with the decrease of surgical complication. The improvements of radical cystectomy, along with the optimization of peri-operative intervention, are providing more curable opportunity to elderly and high operative risk patients of bladder cancer. The breakthrough of basic research on molecular pathogenesis of renal cell carcinoma, leads to the innovative clinical translation of molecular targeted therapy in the treatment of metastatic renal cancer. The great success of research and development on targeted therapy now are attracting more and more clinical and basic researches which possibly lead to promising novel treatments to urological malignance in the coming future. For the best clinical practice in urological oncology, it is necessary to pay tremendous attention on the advance of both clinical study and laboratory research, which would be the better way to more effectively improve the survival and prognosis of the patients of urological malignance with comprehensive treatments.