维生素 C 可提高体细胞核重编程的质量。
Vitamin C improves the quality of somatic cell reprogramming.
机构信息
Stem Cell and Cancer Biology Group at the Key Laboratory of Regenerative Biology, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China.
出版信息
Nat Genet. 2012 Mar 28;44(4):366-7. doi: 10.1038/ng.2222.
DOI:10.1038/ng.2222
PMID:22456737
Abstract
The reprogramming of somatic cells to a pluripotent state is prone to errors that could hamper the use of this technology. A new study now shows that vitamin C enhances the quality of somatic cell reprogramming in mice, highlighting the possibility that further manipulation of culture conditions could improve this technology for regenerative medicine.
摘要
体细胞重编程为多能状态容易出错，这可能会阻碍这项技术的应用。一项新的研究表明，维生素 C 可提高小鼠体细胞重编程的质量，这突出表明进一步对培养条件进行操作可能会提高这项再生医学技术。
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