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预测急性哮喘患儿的住院需求。

Predicting the need for hospitalization in children with acute asthma.

作者信息

Kerem E, Tibshirani R, Canny G, Bentur L, Reisman J, Schuh S, Stein R, Levison H

机构信息

Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.

出版信息

Chest. 1990 Dec;98(6):1355-61. doi: 10.1378/chest.98.6.1355.

Abstract

In an attempt to identify factors which influence the decision of physicians to admit patients with acute asthma to the hospital, we studied prospectively 200 children (age 5.6 +/- 3.1 years, mean +/- SD) presenting to our emergency room with acute asthma. The children were assessed on arrival, and on disposition from the Emergency Room by one of the investigators. After obtaining historic data, a clinical score was assigned, and oxygen saturation and pulmonary function were measured. Of the 134 (67 percent) children who were discharged home from the Emergency Room, five returned within seven days and one was subsequently admitted. The clinical score on disposition was the sole variable found to best predict the decision for hospitalization (sensitivity 73 percent, specificity 95 percent). Of the variables obtained at presentation, the resulting decision tree found the clinical score to predict the decision for hospitalization (sensitivity 79 percent, specificity 75 percent). When the individual components of the clinical score were analyzed, the degree of dyspnea, as assessed by the investigator, was chosen as the rule to predict the hospitalization decision (sensitivity 88 percent, specificity 71 percent). We conclude that the decision with respect to the need for hospitalization in acute childhood asthma, is in practice based mainly on careful clinical evaluation. Pulmonary function and SaO2 measurements, although helpful adjuncts in the assessment of acute asthma, do not appear to contribute to the identification of patients who need hospital admission.

摘要

为了确定影响医生决定将急性哮喘患儿收住入院的因素,我们对前瞻性研究了200名因急性哮喘前来我院急诊室就诊的儿童(年龄5.6±3.1岁,均值±标准差)。患儿到达时及从急诊室转出时均由一名研究人员进行评估。获取病史数据后,给出临床评分,并测量血氧饱和度和肺功能。在从急诊室出院回家的134名儿童(67%)中,5名在7天内复诊,1名随后入院。发现转出时的临床评分是最能预测住院决策的唯一变量(敏感性73%,特异性95%)。在就诊时获取的变量中,生成的决策树显示临床评分可预测住院决策(敏感性79%,特异性75%)。分析临床评分的各个组成部分时,研究人员评估的呼吸困难程度被选为预测住院决策的指标(敏感性88%,特异性71%)。我们得出结论,对于儿童急性哮喘是否需要住院的决策,实际上主要基于仔细的临床评估。肺功能和血氧饱和度测量虽然在评估急性哮喘时是有用的辅助手段,但似乎无助于确定需要住院的患者。

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