Institute of Nutraceuticals and Functional Foods, Laval University, Pavillon des Services, Bureau 2602, 2440, Boulevard Hochelaga, Québec, Canada G1V 0A6.
Maturitas. 2012 Jun;72(2):113-6. doi: 10.1016/j.maturitas.2012.03.001. Epub 2012 Mar 28.
Cardiovascular disease (CVD) is the predominant cause of mortality in type 2 diabetic (T2DM) patients. Dyslipidemia is a modifiable risk factor that should be treated early for CVD prevention. Further, dietary supplement intake is increasing in popularity worldwide. This review examines the recent meta-analyses and clinical studies on dietary supplements, specifically psyllium, garlic and green tea, on plasma lipids levels and glycemic control, as well as other potential CVD risk factors in T2DM patients. Generally, results demonstrate that psyllium supplements improve lipid profiles as well as glycemic control beyond a traditional diet in patients with T2DM. On the other hand, the results on the usefulness of garlic and green tea supplementation for dyslipidemia and hyperglycemia are uncertain. Overall, the addition of dietary supplements may be a therapeutic alternative to lower CVD risk factors in T2DM; however, more well-designed intervention studies are needed to assess the benefit of these dietary supplements.
心血管疾病（CVD）是 2 型糖尿病（T2DM）患者死亡的主要原因。血脂异常是一种可改变的危险因素，应早期进行治疗以预防 CVD。此外，膳食补充剂的摄入在全球范围内越来越受欢迎。本综述考察了最近关于膳食补充剂，特别是车前子、大蒜和绿茶，对 T2DM 患者的血浆脂质水平和血糖控制以及其他潜在 CVD 危险因素的荟萃分析和临床研究。总的来说，结果表明，车前子补充剂可改善 T2DM 患者的血脂谱和血糖控制，效果优于传统饮食。另一方面，关于大蒜和绿茶补充剂在血脂异常和高血糖方面的有效性的结果尚不确定。总的来说，膳食补充剂的添加可能是降低 T2DM 患者 CVD 危险因素的一种治疗选择；然而，需要更多精心设计的干预研究来评估这些膳食补充剂的益处。
