Spagnoli Anna Maria, Fino Pasquale, Fioramonti Paolo, Corrias Federico, Lo Torto Federico, Scuderi Nicolò
Department of Dermatology and Plastic, Reconstructive and Aesthetic Surgery, University of Rome La Sapienza Policlinico Umberto I, Rome, Italy.
Ann Ital Chir. 2012 Mar-Apr;83(2):103-7.
In the present study, we investigated effects of a local anesthetic, in the treatment of pathologic scars.
this retrospective report describes our experience with 97 patients who underwent lidocaine 2% injections in surgical scars of the hand. The results were evaluated using 4 parameters: cutaneous structure, pain, thikness and colour of the scar.
The mean outcome was the pain control. 2 out of 97 showed a 100% improvement in all the parameters. In 95 of 97 patients the improvement was between 60-100%.
Lidocaine controls different pathways of inflammation. Flogosis is the first phase of cicatrization and so lidocaine could be used in the treatment of pathologic scars. A previous study confirms the role of lidocaine, injected to control the pillar pain in the carpal tunnel's surgery in the improvement of scars.
Lidocaine, as neuromodulation treatment, acts on inflammation, temperature, perfusion and partial pressure of oxygen.
在本研究中，我们调查了一种局部麻醉剂在病理性瘢痕治疗中的效果。
本回顾性报告描述了我们对97例手部手术瘢痕接受2%利多卡因注射治疗患者的经验。使用4个参数评估结果：皮肤结构、疼痛、瘢痕厚度和颜色。
平均结果是疼痛得到控制。97例中有2例在所有参数上均有100%的改善。97例患者中有95例的改善在60%-100%之间。
利多卡因可控制炎症的不同途径。炎症是瘢痕形成的第一阶段，因此利多卡因可用于病理性瘢痕的治疗。先前的一项研究证实了在腕管手术中注射利多卡因以控制柱状疼痛对瘢痕改善的作用。
作为神经调节治疗，利多卡因作用于炎症、温度、灌注和氧分压。
