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巨大腹膜后脂肪肉瘤。5例报告。

Giant retroperitoneal liposarcoma. Report of 5 cases.

作者信息

Makni Amin, Triki Aymen, Fetirich Fadhel, Ksantini Rachid, Chebbi Faouzi, Jouini Mohamed, Kacem Montassar, Ben Safta Zoubeir

机构信息

Department of General Surgery A, La Rabta Hospital, Tunis, Tunisia.

出版信息

Ann Ital Chir. 2012 Mar-Apr;83(2):161-6.

Abstract

BACKGROUND

Liposarcoma is the most frequent histopathological variety of the retroperitoneum, surgery is the gold standard for treatment.

CLINICAL SERIES

We report, retrospectively over 7 years (2000-2006), 5 cases (four men and one woman, the mean age was 48 years) of giant retroperitoneal liposarcomas and study their clinical characteristics intra operatively findings and course evolution. None of our patients had a percutaneous biopsy of his tumour. Surgery was indicated to all patients. Resection was performed in 4 cases (we performed a bloc resection in three cases and a simple tumour resection in one case), and in one case, abstention was decided. None of patients had an adjuvant therapy Three of the patients still alive after the follow up of 2, 3 and 4 years.

CONCLUSION

Retroperitoneal liposarcomas represent a unique situation and require a more aggressive surgical approach including multiple resections for recurrences. Based on the ability of the patient to tolerate the procedure, surgery is suggested to evaluate resectability of the tumor. We must take into consideration whether prolonged survival will be attained and tumor removal will result in palliation of symptoms.

摘要

背景

脂肪肉瘤是腹膜后最常见的组织病理学类型,手术是其治疗的金标准。

临床病例系列

我们回顾性报告了7年(2000 - 2006年)间5例巨大腹膜后脂肪肉瘤病例(4例男性,1例女性,平均年龄48岁),并研究了其临床特征、术中发现及病程演变。我们所有患者均未对其肿瘤进行经皮活检。所有患者均接受了手术治疗。4例患者进行了切除手术(3例进行了整块切除,1例进行了单纯肿瘤切除),1例患者决定放弃手术。所有患者均未接受辅助治疗。随访2年、3年和4年后,3例患者仍存活。

结论

腹膜后脂肪肉瘤情况特殊,需要更积极的手术方法,包括对复发病例进行多次切除。根据患者耐受手术的能力,建议通过手术评估肿瘤的可切除性。我们必须考虑是否能实现延长生存期以及肿瘤切除是否会缓解症状。

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