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气动输送系统速度和距离对血标本溶血的影响。

Effect of pneumatic tube delivery system rate and distance on hemolysis of blood specimens.

机构信息

Department of Medical Biochemistry, Dicle University, Diyarbakır, Turkey.

出版信息

J Clin Lab Anal. 2012 Feb;26(2):66-9. doi: 10.1002/jcla.21484.

DOI:10.1002/jcla.21484
PMID:22467320
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6807593/
Abstract

BACKGROUND

We evaluated the effects of pneumatic tube system (PTS) transport rates and distances on routine hematology and coagulation analysis. PTS effects on centrifuged blood samples were also examined.

METHOD

The study was completed at Dicle University Hospital, which has the longest pneumatic tube system in Turkey. Blood samples were collected at three different locations within the hospital and an emergency department, and delivered to the central laboratory by the PTS or a human carrier. Samples were transported at different rates and over varying distances. Each specimen's potassium (K) and lactic dehydrogenase (LDH) levels, in both the serum and plasma, were tracked to monitor hemolysis. Measurements of LDH and K were obtained using heparin or citrate.

RESULT

A positive correlation was observed between distance and hemolysis in serum samples transported at 4.2 m/sec, and at 3.1 m/sec for more than 2200 m (r = 0.774 and r = 0.766, respectively). Distance and hemolysis were also correlated in non-centrifuged samples (r = 0.871). The alterations in plasma LDH and K levels at different rates and PTS lengths were not statistically significant.

CONCLUSION

The rate of hemolysis in PTS transported samples, dependent on PTS length and rate, may seriously affect routine tests of non-centrifuged samples.

摘要

背景

我们评估了气动输送系统 (PTS) 的输送速度和距离对常规血液学和凝血分析的影响。还检查了 PTS 对离心血液样本的影响。

方法

该研究在土耳其最长的气动输送系统的迪亚巴克尔大学医院进行。在医院内的三个不同地点和一个急诊科采集血液样本,并通过 PTS 或人工载体将其输送到中心实验室。样本以不同的速度和不同的距离进行输送。跟踪每个标本的钾 (K) 和乳酸脱氢酶 (LDH) 水平,以监测溶血。使用肝素或柠檬酸盐测量 LDH 和 K。

结果

以 4.2 m/sec 输送的血清样本中,距离与溶血呈正相关,以 3.1 m/sec 输送超过 2200 m 时也呈正相关(r = 0.774 和 r = 0.766)。非离心样本中距离与溶血也相关(r = 0.871)。在不同速度和 PTS 长度下,血浆 LDH 和 K 水平的变化没有统计学意义。

结论

PTS 输送样本的溶血率取决于 PTS 的长度和速度,可能严重影响非离心样本的常规检测。

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