Aono J, Ueda W, Hirakawa M
Department of Anesthesiology & Resuscitology, Kochi Medical School, Nankoku.
Masui. 1990 Sep;39(9):1160-3.
We performed ICG-test (indo-cyanine green test) during surgery to study the effect of isoflurane and enflurane on ICG clearance in human. When the systolic arterial pressure (SAP) was maintained at 70% of the preoperative base line value, a significant decrease in ICG clearance occurred in the patients who received enflurane. Isoflurane, on the contrary, did not cause such a decrease in the ICG clearance. We conclude that isoflurane may restore either the blood flow to the liver or the liver function and the liver may remove ICG from the blood much better under isoflurane than under enflurane.
我们在手术期间进行了吲哚菁绿试验（ICG试验），以研究异氟烷和安氟烷对人体ICG清除率的影响。当收缩动脉压（SAP）维持在术前基线值的70%时，接受安氟烷的患者ICG清除率显著降低。相反，异氟烷并未导致ICG清除率出现这种下降。我们得出结论，异氟烷可能恢复肝脏血流或肝功能，并且在异氟烷麻醉下肝脏从血液中清除ICG的能力可能比在安氟烷麻醉下更好。
