Aono J, Mamiya K, Ueda W, Manabe M
Department of Anesthesiology and Resuscitology, Kochi Medical School, Nankoku.
Masui. 1994 Dec;43(12):1857-60.
We evaluated the effect of dopamine administration (3 micrograms.kg-1.min-1) on ICG-disappearance rate during prone position in 10 patients undergoing elective spinal cord surgery. Anesthesia was maintained with isoflurane and 50% nitrous oxide in oxygen. ICG-disappearance rate was determined at 3 points, i.e., the day before surgery, during prone position and during the administration of dopamine. Systolic arterial pressure showed no significant difference before and during dopamine administration. ICG-disappearance rate during prone position was significantly lower than the preoperative value. However, ICG-disappearance rate showed no significant difference during dopamine administration and preoperative period. We conclude that dopamine administration may attenuate the depressant effect of the prone position on the hepatic blood flow.
我们评估了多巴胺给药（3微克·千克⁻¹·分钟⁻¹）对10例择期脊髓手术患者俯卧位期间吲哚菁绿清除率的影响。麻醉维持采用异氟烷和50%氧化亚氮与氧气混合。吲哚菁绿清除率在3个时间点测定，即手术前一天、俯卧位期间和多巴胺给药期间。多巴胺给药前后收缩动脉压无显著差异。俯卧位期间吲哚菁绿清除率显著低于术前值。然而，多巴胺给药期间与术前相比，吲哚菁绿清除率无显著差异。我们得出结论，多巴胺给药可能减弱俯卧位对肝血流的抑制作用。
