Wagenaar F B M, Maathuis C G B, van Erve R H G P
J Child Orthop. 2011 Apr;5(2):89-95. doi: 10.1007/s11832-010-0309-z. Epub 2010 Dec 14.
Compare conservative and operative treatment in the most severely affected Legg-Perthes disease patients.
29 patients (14 conservative and 15 operative) with 32 affected hips (16 conservative and 16 operative) were evaluated, all Catterall 3 or 4. The conservative group, with a median age-at-onset of 4.8 (range, 2.5-9.5) years, was treated by a rigorous regime of traction in abduction for an average of two years. Follow-up was performed at a median of 28.6 (range, 17.4-31.6) years with a median patient age of 34.1 (range, 19.9-39.3) years. The operative group, with a median age-at-onset of 4.7 (range, 2.0-7.8) years, was treated by femoral varus derotation osteotomy. Follow-up was performed at a median of 14 (range, 8-21.4) years, with a median patient age of 20.7 (range, 12.8-28) years.
Median age-at-onset (P = 0.16) and Catterall classification (P = 0.29) were comparable. No differences could be found for the Stulberg classification (P = 0.83), functional parameters (Harris Hip score and Merle d'Aubigné and Postel), and leg-length differences. Career choices were similar for both patient groups, as well.
Given methodological issues, femoral varus derotation osteotomy did not show apparent better results than the conservative containment regime in Catterall 3 and 4 patients with a median age-at-onset around 4.8 years. This result is fairly similar to recent literature suggesting a conservative approach in most severely affected patients with a young age-at-onset. However, based on unacceptable socioeconomic issues, the conservative regime evaluated in the present study cannot be justified, nowadays.
比较最严重的Legg-Perthes病患者的保守治疗和手术治疗效果。
对29例患者(14例保守治疗,15例手术治疗)的32个患髋(16个保守治疗,16个手术治疗)进行评估,所有患者均为Catterall 3或4级。保守治疗组患者发病年龄中位数为4.8岁(范围2.5 - 9.5岁),采用严格的外展牵引方案治疗,平均治疗两年。随访时间中位数为28.6年(范围17.4 - 31.6年),患者年龄中位数为34.1岁(范围19.9 - 39.3岁)。手术治疗组患者发病年龄中位数为4.7岁(范围2.0 - 7.8岁),采用股骨内翻旋转截骨术治疗。随访时间中位数为14年(范围8 - 21.4年),患者年龄中位数为20.7岁(范围12.8 - 28岁)。
发病年龄中位数(P = 0.16)和Catterall分级(P = 0.29)具有可比性。在Stulberg分级(P = 0.83)、功能参数(Harris髋关节评分、Merle d'Aubigné和Postel评分)以及下肢长度差异方面未发现差异。两组患者的职业选择也相似。
考虑到方法学问题,对于发病年龄中位数约4.8岁的Catterall 3和4级患者,股骨内翻旋转截骨术并未显示出明显优于保守包容治疗方案的效果。这一结果与近期文献中建议对发病年龄较小的最严重患者采用保守治疗的观点相当相似。然而,基于不可接受的社会经济问题,本研究中评估的保守治疗方案如今已不合理。