Ren Shuyue, Bhavsar Tapan, Wurzel John
Department of Pathology and Laboratory Medicine, Temple University Hospital, Philadelphia, Pennsylvania 19140, USA.
Fetal Pediatr Pathol. 2012 Dec;31(6):360-4. doi: 10.3109/15513815.2012.659400. Epub 2012 Apr 2.
In the mirror syndrome, maternal edema mirrors fetal edema. The pathogenesis is unknown. The most common etiologic associations are rhesus isoimmunization, twin-twin transfusion syndrome, and viral infections. Less than 10% of reported cases are associated with congenital anomalies. We report a case due to congenital laryngeal stenosis, which also caused congenital high airway obstruction syndrome (CHAOS), characterized by pulmonary hyperplasia and edema or anasarca, related to airway abnormality. The fetal manifestations of the mirror syndrome and CHAOS overlap, but occurrence of the two in the same patient does not seem to have been reported.
在镜像综合征中，母体水肿反映胎儿水肿。其发病机制尚不清楚。最常见的病因关联是恒河猴血型不合免疫、双胎输血综合征和病毒感染。报告病例中不到10%与先天性畸形有关。我们报告一例由先天性喉狭窄引起的病例，该狭窄还导致先天性高位气道梗阻综合征（CHAOS），其特征为肺增生、水肿或全身水肿，与气道异常有关。镜像综合征和CHAOS的胎儿表现有重叠，但同一患者同时出现这两种情况似乎尚未见报道。
