Department of Genetics, Reproduction, and Fetal Medicine, Institute of Biomedicine of Seville (IBIS), Hospital Universitario Virgen del Rocio/CSIC/University of Seville, Seville, Spain.
Centre for Biomedical Network Research on Rare Diseases (CIBERER), Seville, Spain.
BMC Pregnancy Childbirth. 2018 Apr 6;18(1):85. doi: 10.1186/s12884-018-1718-0.
Mirror syndrome (MS) is a rare obstetric condition usually defined as the development of maternal edema in association with fetal hydrops. The pathogenesis of MS remains unclear and may be misdiagnosed as pre-eclampsia.
We report a case series of MS in which fetal therapy (intrauterine blood transfusion and pleuroamniotic shunt) resulted in fetal as well as maternal favourable course with complete resolution of the condition in both mother and fetus.
Our case series add new evidence to support that early diagnosis of MS followed by fetal therapy and clinical maternal support are critical for a good outcome.
镜像综合征（MS）是一种罕见的产科病症，通常定义为母体水肿与胎儿水肿同时发生。MS 的发病机制尚不清楚，可能被误诊为先兆子痫。
我们报告了一系列 MS 病例，胎儿治疗（宫内输血和胸羊水分流）导致胎儿和母体均出现良好的病程，母婴状况均完全缓解。
我们的病例系列为支持早期诊断 MS，随后进行胎儿治疗和临床母体支持对于良好结局至关重要这一观点提供了新的证据。
