Imura Satoru, Shimada Mitsuo, Saito Yu, Iwahashi Shuichi, Hanaoka Jun, Mori Hiroki, Ikemoto Tetsuya, Morine Yuji, Utsunomiya Tohru
Department of Surgery, University of Tokushima, Tokushima, Japan.
Hepatogastroenterology. 2012 May;59(115):863-5. doi: 10.5754/hge10081.
Hemophagocytic syndrome (HPS) is a rare but serious complication that is associated with hypercytokinemia caused by activated T lymphocytes and macrophages in immunologically compromised patients. Living donor liver transplantation (LDLT) between adults has been performed to compensate for the shortage of available organs. There have been some reports of HPS after LDLT but its prognosis is disappointingly poor. Herein, we report a case of HPS in a 53-year-old woman who underwent LDLT using a left lobe graft. HPS was diagnosed on postoperative day 6 and successfully treated with a steroid pulse. HPS is a fatal complication in immunologically compromised patients but its early diagnosis and appropriate treatment can lead to an improved outcome.
噬血细胞综合征（HPS）是一种罕见但严重的并发症，与免疫功能低下患者中活化的T淋巴细胞和巨噬细胞引起的高细胞因子血症相关。成人活体肝移植（LDLT）已被用于弥补可用器官的短缺。已有一些关于LDLT后发生HPS的报道，但其预后令人失望地差。在此，我们报告一例53岁女性在接受左叶移植的LDLT后发生HPS的病例。HPS于术后第6天被诊断出，并通过类固醇冲击成功治疗。HPS在免疫功能低下患者中是一种致命的并发症，但其早期诊断和适当治疗可改善预后。
