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在炎性关节病中使用自体肌腱或聚-L-丙交酯植入物置入重建第一掌腕关节:一项前瞻性临床试验。

Reconstruction of the trapeziometacarpal joint in inflammatory joint disease using interposition of autologous tendon or poly-L-D-lactic acid implants: a prospective clinical trial.

作者信息

Tiihonen Raine P, Skyttä Eerik T, Kaarela Kalevi, Ikävalko Mikko, Belt Eero A

机构信息

Department of Orthopaedics, Päijät-Häme Central Hospital, Keskussairaalankatu 7, Lahti, Finland.

出版信息

J Plast Surg Hand Surg. 2012 Apr;46(2):113-9. doi: 10.3109/2000656X.2012.669202.

DOI:10.3109/2000656X.2012.669202
PMID:22471260
Abstract

Interposition arthroplasty with bioreplaceable poly-L-D-lactic acid (PLDLA) implants has yielded promising results in reconstruction of rheumatoid hands. In this prospective clinical study we compared the PLDLA implant arthroplasty (n = 17) with that of tendon interposition (n = 12) for destruction of the trapeziometacarpal joint in arthritic patients. There was no significant difference between the two groups preoperatively. At one-year follow-up, the mean pain and function scores were 5 and 13 in the PLDLA group, and 19 and 43 in the tendon interposition group, respectively. At one-year follow-up the visual analogue scale (VAS) for function of the PLDLA group differed significantly from that of the tendon interposition group (p = 0.03). This difference was not found at three months postoperatively, and disappeared again at two-year follow-up. Otherwise, no significant difference was found between the groups in the pain or function scores, functional tests, or range of movement. Bioreplaceable interposition arthroplasty works at least as well as tendon interposition. The operation is easier.

摘要

采用可生物替代的聚-L-D-乳酸(PLDLA)植入物进行间置关节成形术在类风湿性手部重建中取得了令人鼓舞的结果。在这项前瞻性临床研究中,我们比较了PLDLA植入物关节成形术(n = 17)和肌腱间置术(n = 12)对关节炎患者第一掌腕关节破坏的治疗效果。两组患者术前无显著差异。在一年的随访中,PLDLA组的平均疼痛和功能评分分别为5分和13分,肌腱间置组分别为19分和43分。在一年的随访中,PLDLA组的功能视觉模拟量表(VAS)与肌腱间置组有显著差异(p = 0.03)。术后三个月未发现这种差异,在两年随访时差异再次消失。此外,两组在疼痛或功能评分、功能测试或活动范围方面未发现显著差异。可生物替代的间置关节成形术至少与肌腱间置术效果相同,且手术操作更简便。

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