Department of Urology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
J Endourol. 2012 Aug;26(8):1070-4. doi: 10.1089/end.2012.0042. Epub 2012 Jun 13.
Effective stone comminution during shockwave lithotripsy (SWL) is dependent on precise three-dimensional targeting of the shockwave. Respiratory motion, imprecise targeting or shockwave alignment, and stone movement may compromise treatment efficacy. The purpose of this study was to evaluate the accuracy of shockwave targeting during SWL treatment and the effect of motion from respiration.
Ten patients underwent SWL for the treatment of 13 renal stones. Stones were targeted fluoroscopically using a Healthtronics Lithotron (five cases) or Dornier Compact Delta II (five cases) shockwave lithotripter. Shocks were delivered at a rate of 1 to 2 Hz with ramping shockwave energy settings of 14 to 26 kV or level 1 to 5. After the low energy pretreatment and protective pause, a commercial diagnostic ultrasound (US) imaging system was used to record images of the stone during active SWL treatment. Shockwave accuracy, defined as the proportion of shockwaves that resulted in stone motion with shockwave delivery, and respiratory stone motion were determined by two independent observers who reviewed the ultrasonographic videos.
Mean age was 51 ± 15 years with 60% men, and mean stone size was 10.5 ± 3.7 mm (range 5-18 mm). A mean of 2675 ± 303 shocks was delivered. Shockwave-induced stone motion was observed with every stone. Accurate targeting of the stone occurred in 60% ± 15% of shockwaves.
US imaging during SWL revealed that 40% of shockwaves miss the stone and contribute solely to tissue injury, primarily from movement with respiration. These data support the need for a device to deliver shockwaves only when the stone is in target. US imaging provides real-time assessment of stone targeting and accuracy of shockwave delivery.
在体外冲击波碎石术(SWL)中,有效碎石取决于冲击波的精确三维靶向。呼吸运动、靶向不精确或冲击波定位不当以及结石移动都可能影响治疗效果。本研究旨在评估 SWL 治疗过程中冲击波靶向的准确性以及呼吸运动的影响。
10 例患者因 13 个肾结石接受 SWL 治疗。使用 Healthtronics Lithotron(5 例)或 Dornier Compact Delta II(5 例)冲击波碎石机进行透视下靶向定位。冲击波以 1 至 2Hz 的速度传递,能量设置逐渐增加至 14 至 26kV 或 1 至 5 级。在低能量预处理和保护性暂停后,使用商业诊断超声(US)成像系统记录主动 SWL 治疗过程中结石的图像。通过两位独立观察者查看超声视频来确定冲击波的准确性(定义为冲击波传递导致结石运动的比例)和呼吸相关的结石运动。
平均年龄为 51±15 岁,男性占 60%,结石平均大小为 10.5±3.7mm(范围 5-18mm)。共传递了 2675±303 次冲击波。每个结石都观察到冲击波引起的结石运动。有 60%±15%的冲击波能够准确靶向结石。
SWL 期间的 US 成像显示,40%的冲击波未能靶向结石,仅导致组织损伤,主要是由于呼吸运动导致的。这些数据支持仅在结石处于靶位时传递冲击波的设备的需求。US 成像可实时评估结石靶向和冲击波传递的准确性。