Pyo Dongjin, Yoo Jisun
Department of Chemistry, Kangwon National University, Chunchon, South Korea.
J Immunoassay Immunochem. 2012;33(2):203-22. doi: 10.1080/15321819.2011.618863.
During the last decade, immunochromatographic techniques, in particular fluorescence labeled immunochromatography, have become more popular for the determination of low concentrations of analytes. It offers several potential advantages including highly sensitive detection and wide applications in clinical chemistry, bioanalysis, and environmental analysis. Currently, fluorescence labeled immunochromatography is not the exclusive preserve for a few specialists who are well experienced with antigen-antibody analysis, since the recent developments in fluorescence labeled immunochromatography have become widespread, from simple screening application to quantitative analysis of analytes. In this review, we assembled recent advances in the development and applications of fluorescence labeled immunochromatography techniques, considering their potential benefits in the future.
在过去十年中,免疫色谱技术,尤其是荧光标记免疫色谱法,在测定低浓度分析物方面变得越来越流行。它具有几个潜在优势,包括高灵敏度检测以及在临床化学、生物分析和环境分析中的广泛应用。目前,荧光标记免疫色谱法不再是少数对抗抗原抗体分析经验丰富的专家的专属领域,因为荧光标记免疫色谱法的最新进展已广泛应用,从简单的筛查应用到分析物的定量分析。在本综述中,我们汇总了荧光标记免疫色谱技术在开发和应用方面的最新进展,并考虑了它们未来的潜在益处。