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青少年复发性呼吸道乳头状瘤病

Juvenile-onset recurrent respiratory papillomatosis.

作者信息

Maturo Stephen C, Hartnick Christopher J

机构信息

Department of Otolaryngology, San Antonio Military Medical Center, Fort Sam Houston, TX, USA.

出版信息

Adv Otorhinolaryngol. 2012;73:105-8. doi: 10.1159/000334457. Epub 2012 Mar 29.

DOI:10.1159/000334457
PMID:22472239
Abstract

Juvenile-onset recurrent respiratory papillomatosis, caused by the human papilloma virus, is the most common benign neoplasm of the larynx in children. Recurrent respiratory papillomatosis is relatively rare, but it can have a significant impact on afflicted children and their family's quality of life as dysphonia and multiple surgical procedures are hallmarks of this disease. The current standard of care is surgical therapy with a goal of complete papilloma removal and preservation of normal structures. The technique in this atlas combines both the microdebrider and the pulse KTP laser. The microdebrider allows for rapid removal of bulky lesions without the risk of thermal injury, yet it cannot provide precise removal in areas such as the anterior commissure and ventricle. The pulse KTP laser allows for removal of sessile lesions and in sensitive areas such as the vocal folds. The authors describe this technique as well as discuss adjuvant therapies and pearls for success.

摘要

青少年复发性呼吸道乳头状瘤病由人乳头瘤病毒引起,是儿童喉部最常见的良性肿瘤。复发性呼吸道乳头状瘤病相对罕见,但由于声音嘶哑和多次外科手术是该病的特征,它会对患病儿童及其家庭的生活质量产生重大影响。当前的护理标准是手术治疗,目标是完全切除乳头状瘤并保留正常结构。本图谱中的技术结合了微型清创器和脉冲KTP激光。微型清创器可快速切除大块病变而无热损伤风险,但在前联合和脑室等区域无法进行精确切除。脉冲KTP激光可用于切除无蒂病变以及在声带等敏感区域进行操作。作者描述了该技术,并讨论了辅助治疗方法和成功要点。

相似文献

1
Juvenile-onset recurrent respiratory papillomatosis.青少年复发性呼吸道乳头状瘤病
Adv Otorhinolaryngol. 2012;73:105-8. doi: 10.1159/000334457. Epub 2012 Mar 29.
2
[Clinical and molecular biology studies of respiratory papillomatosis].[呼吸道乳头状瘤病的临床与分子生物学研究]
Laryngorhinootologie. 1998 Mar;77(3):157-64. doi: 10.1055/s-2007-996952.
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Investigation of the presence of HPV on KTP laser fibers following KTP laser treatment of papilloma.KTP激光治疗乳头瘤后KTP激光纤维上HPV存在情况的调查。
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Juvenile recurrent respiratory papilloma: variable intersurgical intervals.青少年复发性呼吸道乳头瘤:可变的手术间隔。
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J Med Virol. 2013 Aug;85(8):1447-58. doi: 10.1002/jmv.23615.
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[Clinical and molecular biology studies of laryngeal papillomatosis].喉乳头状瘤病的临床与分子生物学研究
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Dan Med J. 2017 Dec;64(12).
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Human Papillomavirus 16 E2 Interaction with TopBP1 Is Required for E2 and Viral Genome Stability during the Viral Life Cycle.人乳头瘤病毒 16 E2 与 TopBP1 的相互作用是病毒生命周期中 E2 和病毒基因组稳定性所必需的。
J Virol. 2023 Mar 30;97(3):e0006323. doi: 10.1128/jvi.00063-23. Epub 2023 Feb 22.
2
Comparing KTP and CO laser excision for recurrent respiratory papillomatosis: A systematic review.比较KTP激光与CO激光切除复发性呼吸道乳头状瘤病:一项系统评价。
Laryngoscope Investig Otolaryngol. 2022 Jul 16;7(4):970-981. doi: 10.1002/lio2.871. eCollection 2022 Aug.