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机器人辅助腹腔镜子宫肌瘤切除术:加拿大的经验

Robotically assisted laparoscopic myomectomy: a Canadian experience.

作者信息

Mansour Fady W, Kives Sari, Urbach David R, Lefebvre Guylaine

机构信息

Department of Gynecology, St. Michael's Hospital, University of Toronto, Toronto ON; Department of Gynecology, McGill University Health Centre, Montreal QC.

Department of Gynecology, St. Michael's Hospital, University of Toronto, Toronto ON.

出版信息

J Obstet Gynaecol Can. 2012 Apr;34(4):353-358. doi: 10.1016/S1701-2163(16)35216-1.

Abstract

OBJECTIVE

To compare operative and immediate postoperative outcomes of robotically assisted laparoscopic myomectomy (RALM) and open myomectomy.

METHODS

We conducted a retrospective review of 38 cases of RALM performed in women of reproductive age with symptomatic uterine fibroids between October 2008 and February 2011. Twenty-one cases of open myomectomy were used as historical controls. Operative and immediate postoperative outcomes were compared. Data analysis was performed using Student t test, chi-square test, and analysis of covariance where appropriate.

RESULTS

The two groups were comparable in age, body mass index, parity, and symptoms. Up to 12 fibroids were resected robotically with a mean diameter of 9.1 ± 2.0 cm and a mean weight of 389 ± 170 g (range 73 to 900 g). RALM was associated with less blood loss (decrease in hemoglobin concentration 25.6 ± 12.0g/L) than open myomectomy (37.7 ± 20.1 g/L) (P = 0.018). Adjusting for baseline levels, postoperative hemoglobin levels were 99 g/L and 88 g/L in the robotic and open groups, respectively (P = 0.005). RALM was associated with shorter hospitalization (1.2 ± 0.5 vs. 2.5 ± 0.6 days, P < 0.001) and longer operating times (189.7 ± 71.5 vs. 92.5 ± 33.0 minutes, P < 0.001). Three patients in the open myomectomy group and one in the robotic group required blood transfusion. One patient in the robotic group developed lumbar plexopathy postoperatively.

CONCLUSION

Robotically assisted laparoscopic myomectomy is associated with less blood loss and shorter hospital stay than myomectomy by laparotomy. Accumulating evidence of the risks and benefits of RALM will contribute to enhancing access to this technology on the part of women and their surgeons.

摘要

目的

比较机器人辅助腹腔镜子宫肌瘤切除术(RALM)与开腹子宫肌瘤切除术的手术及术后即刻效果。

方法

我们对2008年10月至2011年2月期间为有症状的育龄期子宫肌瘤女性施行的38例RALM进行了回顾性研究。将21例开腹子宫肌瘤切除术作为历史对照。比较手术及术后即刻效果。在适当情况下,使用学生t检验、卡方检验和协方差分析进行数据分析。

结果

两组在年龄、体重指数、产次和症状方面具有可比性。通过机器人手术切除多达12个肌瘤,平均直径为9.1±2.0cm,平均重量为389±170g(范围73至900g)。与开腹子宫肌瘤切除术相比,RALM的失血量较少(血红蛋白浓度下降25.6±12.0g/L)(37.7±20.1g/L)(P=0.018)。调整基线水平后,机器人手术组和开腹手术组术后血红蛋白水平分别为99g/L和88g/L(P=0.005)。RALM与住院时间缩短相关(1.2±0.5天对2.5±0.6天,P<0.001),手术时间较长(189.7±71.5分钟对92.5±33.0分钟,P<0.001)。开腹子宫肌瘤切除术组有3例患者和机器人手术组有1例患者需要输血。机器人手术组有1例患者术后发生腰丛神经病变。

结论

与开腹子宫肌瘤切除术相比,机器人辅助腹腔镜子宫肌瘤切除术失血量更少,住院时间更短。RALM风险和益处的证据不断积累,将有助于女性及其外科医生更多地采用这项技术。

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