Department of Animal Physiology, University of Warmia and Mazury, Olsztyn, Poland.
Reprod Biol. 2012 Mar;12(1):81-9. doi: 10.1016/s1642-431x(12)60079-5.
The aim of this study was to investigate the expression of aquaporins (AQPs) in uterine tissues of premenopausal women. We demonstrated for the first time the expression of AQP1, AQP5 and AQP9 in uterine leiomyomata and in the adjacent normal endometrium and myometrium. The expression of AQP1 and 5 was higher in leiomyomata than in unaffected uteri. AQP9 was expressed only in the unaffected endometrium. It is possible that AQP1 and AQP5 contribute to the formation of leiomyomata in premenopausal women.
本研究旨在探讨水通道蛋白（AQPs）在绝经前妇女子宫组织中的表达。我们首次证明了 AQP1、AQP5 和 AQP9 在子宫肌瘤以及相邻的正常子宫内膜和子宫肌层中的表达。AQP1 和 AQP5 的表达在子宫肌瘤中高于未受影响的子宫。AQP9 仅在未受影响的子宫内膜中表达。AQP1 和 AQP5 可能有助于绝经前妇女子宫肌瘤的形成。
