Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands. ernestpauwels @ gmail.com
Med Princ Pract. 2012;21(6):508-15. doi: 10.1159/000337404. Epub 2012 Mar 30.
Over the past two decades technical advances and improvements have made computed tomography (CT) a valuable and essential tool in the array of diagnostic imaging modalities. CT uses ionizing radiation (X-rays) which may damage DNA and increase the risk of carcinogenesis. This is especially pertinent in pediatric CT as children are more radiosensitive and have a longer life expectancy than adults. The purpose of this paper is to review and elucidate the potential harmful effects of ionizing radiation in terms of solid cancer induction from pediatric CT scanning. In the light of scientific and technical developments, we will also discuss the possible strategies and ongoing efforts to reduce CT radiation exposure in pediatric patients. In this context, we will not ignore the fact that a well-justified CT scan may exceed its risk and have a favorable impact.
在过去的二十年中，技术的进步和改进使计算机断层扫描（CT）成为诊断成像方式中非常有价值和必不可少的工具。CT 使用电离辐射（X 射线），这可能会损害 DNA 并增加致癌风险。这在儿科 CT 中尤为相关，因为儿童比成人对辐射更敏感，并且预期寿命更长。本文的目的是回顾和阐明电离辐射对儿科 CT 扫描引起实体癌的潜在有害影响。根据科学和技术的发展，我们还将讨论降低儿科患者 CT 辐射暴露的可能策略和正在进行的努力。在这种情况下，我们不会忽视这样一个事实，即一个有充分理由的 CT 扫描可能会超过其风险并产生有利影响。
