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采用医用水蛭疗法进行皮瓣挽救的结果。

Outcomes of flap salvage with medicinal leech therapy.

机构信息

Division of Plastic Surgery, Baylor College of Medicine, Houston, TX, USA.

出版信息

Microsurgery. 2012 Jul;32(5):351-7. doi: 10.1002/micr.21960. Epub 2012 Mar 31.

Abstract

Medicinal leech therapy (MLT) to salvage venous congestion in native skin and local flaps is commonly practiced. However, the role of MLT in compromised regional and free flaps remains unclear. Leeches were used in 39 patients to treat venous congestion in native skin (n = 5), local flaps (n = 6), regional flaps (n = 14), and free flaps (n = 14). There were no total losses in patients with compromised native skin or local flaps. One patient who had received a radial forearm free flap expired before flap outcome could be assessed, and was excluded from analysis. Of the remaining 27 regional and free flaps, 33.3% were salvaged, 33.3% were partially salvaged, and 33.3% were lost. Means of 38.3 ± 34.0, 101.0 ± 11.2, and 157.9 ± 224.4 leeches and 1.7 ± 3.6, 3.2 ± 4.4, and 5.6 ± 5.2 units of blood were required for the salvaged, partially salvaged, and lost groups, respectively. Twenty-two patients required blood transfusion (57.9%). No patients developed wound infection with Aeromonas hydrophilia. Two patients developed donor site hematomas, and four patients developed recipient site hematomas. MLT is efficacious in congested native skin and local flaps. Some regional and free flaps can be totally or partially salvaged. However, the morbidity of MLT must be weighed against the risks of flap loss.

摘要

医学水蛭疗法(MLT)常用于治疗原生皮肤和局部皮瓣的静脉淤血,但在有问题的区域性和游离皮瓣中的作用尚不清楚。39 名患者使用水蛭治疗原生皮肤(n=5)、局部皮瓣(n=6)、区域性皮瓣(n=14)和游离皮瓣(n=14)的静脉淤血。有问题的原生皮肤或局部皮瓣的患者均未发生全部损失。1 名接受游离前臂桡动脉皮瓣的患者在评估皮瓣结果前死亡,被排除在分析之外。在剩余的 27 个区域性和游离皮瓣中,33.3%被挽救,33.3%部分挽救,33.3%丢失。挽救组、部分挽救组和丢失组分别需要 38.3±34.0、101.0±11.2 和 157.9±224.4 只水蛭和 1.7±3.6、3.2±4.4 和 5.6±5.2 单位的血液。22 名患者需要输血(57.9%)。没有患者因嗜水气单胞菌感染而发生伤口感染。2 名患者发生供区血肿,4 名患者发生受区血肿。MLT 对充血的原生皮肤和局部皮瓣有效。一些区域性和游离皮瓣可以完全或部分挽救。然而,必须权衡 MLT 的发病率与皮瓣丢失的风险。

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