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面部整形与重建手术中失败的皮瓣:医用水蛭的作用

The failing flap in facial plastic and reconstructive surgery: role of the medicinal leech.

作者信息

Utley D S, Koch R J, Goode R L

机构信息

Division of Otolaryngology/Head and Neck Surgery, Facial Plastic and Reconstructive Surgery, Stanford University Medical Center, Palo Alto Veterans Administration Health Care System, California 94305-5328, USA.

出版信息

Laryngoscope. 1998 Aug;108(8 Pt 1):1129-35. doi: 10.1097/00005537-199808000-00005.

Abstract

OBJECTIVE

To review the use of the medicinal leech, Hirudo medicinalis, in salvaging the failing, venous-congested flap. A protocol for the use of leeches is presented. Four illustrative cases of failing flaps (pectoralis major, midline forehead, and temporalis) are presented.

STUDY DESIGN

Literature review comprised of MEDLINE search 1965 to present. Retrospective review of four cases involving the management of the failing, venous-congested flap.

METHODS

A retrospective review of four cases of failing, venous-congested flaps was performed.

RESULTS

The authors' experience, as well as the data from the reviewed medical literature, demonstrates the importance of early intervention in order to salvage the failing, venous-congested flap. Leeches are an immediate and efficacious treatment option.

CONCLUSIONS

  1. Review of the literature indicates that the survival of the compromised, venous-congested flap is improved by early intervention with the medicinal leech. H medicinalis injects salivary components that inhibit both platelet aggregation and the coagulation cascade. The flap is decongested initially as the leech extracts blood and is further decongested as the bite wound oozes after the leech detaches. 2. When a flap begins to fail, salvage of that flap demands early recognition of reversible processes, such as venous congestion. The surgeon must be familiar with the use of leeches and should consider their use early, since flaps demonstrate significantly decreased survival after 3 hours if venous congestion is not relieved. In the four cases presented, a standardized protocol facilitated early leech use and provided for the psychological preparation of the patient, availability of leeches, and an antibiotic prophylaxis regimen. 3. The complications associated with leech use can be minimized with antibiotic therapy, wound care, and hematocrit monitoring. 4. The use of the medicinal leech for salvage of the venous-congested flap is a safe, efficacious, economical, and well-tolerated intervention.
摘要

目的

回顾药用蚂蟥(医蛭)在挽救濒临坏死、静脉淤血皮瓣中的应用。提出了蚂蟥使用方案。介绍了4例濒临坏死皮瓣(胸大肌、前额中线和颞肌皮瓣)的病例。

研究设计

文献综述包括1965年至今的MEDLINE检索。对4例涉及处理濒临坏死、静脉淤血皮瓣的病例进行回顾性分析。

方法

对4例濒临坏死、静脉淤血皮瓣病例进行回顾性分析。

结果

作者的经验以及综述医学文献中的数据表明,早期干预对于挽救濒临坏死、静脉淤血皮瓣至关重要。蚂蟥是一种即时且有效的治疗选择。

结论

  1. 文献综述表明,早期使用药用蚂蟥干预可提高受损、静脉淤血皮瓣的存活率。医蛭注入的唾液成分可抑制血小板聚集和凝血级联反应。蚂蟥吸血时皮瓣最初得以减轻充血,蚂蟥脱离后咬伤处渗血时皮瓣进一步减轻充血。2. 当皮瓣开始出现坏死迹象时,挽救该皮瓣需要早期识别可逆过程,如静脉淤血。外科医生必须熟悉蚂蟥的使用方法,并且应尽早考虑使用,因为如果静脉淤血得不到缓解,皮瓣在3小时后存活率会显著降低。在所介绍的4例病例中,标准化方案便于早期使用蚂蟥,并为患者做好心理准备、准备好蚂蟥以及制定抗生素预防方案。3. 通过抗生素治疗、伤口护理和血细胞比容监测,可将与使用蚂蟥相关的并发症降至最低。4. 使用药用蚂蟥挽救静脉淤血皮瓣是一种安全、有效、经济且耐受性良好的干预措施。

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