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免疫系统与骨骼之间的相互作用。

Interactions between the immune system and bone.

作者信息

D'Amelio Patrizia, Fornelli Giorgia, Roato Ilaria, Isaia Giovanni Carlo

机构信息

Patrizia D'Amelio, Giorgia Fornelli, Giovanni Carlo Isaia, Department of Surgical and Medical Disciplines, Section of Gerontology, University of Torino, 10126 Torino, Italy.

出版信息

World J Orthop. 2011 Mar 18;2(3):25-30. doi: 10.5312/wjo.v2.i3.25.

Abstract

The relationship between the immune system, estrogen deficiency and bone loss is an intriguing and, as yet, unexplained challenge of the past two decades. Here we summarize the evidence that links immune cells, inflammation, cytokine production and osteoclast formation and activity with particular regard to humans.

摘要

免疫系统、雌激素缺乏与骨质流失之间的关系是过去二十年来一个引人关注但尚未得到解释的难题。在此,我们总结了将免疫细胞、炎症、细胞因子产生以及破骨细胞形成和活性联系起来的证据,尤其侧重于人类方面。

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