Alegría-Landa Victoria, Kutzner Heinz, Requena Luis
Department of Dermatology, Fundación Jiménez Díaz, Universidad Autónoma, Madrid, Spain.
Dermatopathologie Laboratory, Friedrichshafen, Germany.
Am J Dermatopathol. 2018 Jul;40(7):e104-e106. doi: 10.1097/DAD.0000000000001086.
Poromas are benign cutaneous adnexal neoplasms with differentiation toward excretory ducts of eccrine and apocrine glands. They are mainly composed of solid aggregates of small, monomorphous, round, and basophilic poroid cells, with a lower proportion of larger, squamous, eosinophilic cuticular cells, which are lining ductal structures with an eosinophilic luminal cuticle. In most cases of poromas, cuticular cells represent a small proportion of the neoplastic aggregates. We report 2 poromas mostly composed of cuticular cells, and on the basis of these findings, we have named cuticuloma to this histopathologic variant of poroma.
汗孔瘤是一种良性皮肤附属器肿瘤，向小汗腺和大汗腺的排泄管分化。它们主要由小的、形态单一的、圆形的嗜碱性汗孔样细胞的实性团块组成，较大的、鳞状的、嗜酸性的角质形成细胞比例较低，这些细胞衬于具有嗜酸性管腔角质层的导管结构。在大多数汗孔瘤病例中，角质形成细胞在肿瘤性团块中占比小。我们报告了2例主要由角质形成细胞组成的汗孔瘤，并基于这些发现，将汗孔瘤的这种组织病理学变异型命名为角质瘤。
