Chou Shen-Chieh, Chuang Lee-Ming, Lee Shoei-Sheng
Research Center for Biodiversity and Graduate Institute of Ecology and Evolutionary Biology, China Medical University, Taichung 40402, Taiwan.
Nat Prod Commun. 2012 Feb;7(2):221-2.
Gynura divaricata Kitam. subsp. formosana is a folk medicine used as a hypoglycemic agent for diabetes patients in Taiwan. Guided by the hexose transport assay, the hypoglycemic constituents of the aerial part of this plant were disclosed through chromatographic methods. They are fructooligosaccharides, including beta-D-fructofuranose, sucrose, 1-kestose, nystose, and 1(F)-beta-fructofuranosylnystose. The hexose transport assay indicated that nystose was the most potent among these compounds, showing a 46.7% difference from pinitol in the stimulation index at a concentration of 0.5 mg/mL.
台湾白凤菜是一种民间药物，在台湾被用作糖尿病患者的降血糖剂。在己糖转运试验的指导下，通过色谱方法揭示了该植物地上部分的降血糖成分。它们是低聚果糖，包括β-D-呋喃果糖、蔗糖、蔗果三糖、蔗果四糖和1（F）-β-呋喃果糖基蔗果四糖。己糖转运试验表明，蔗果四糖在这些化合物中活性最强，在浓度为0.5mg/mL时，其刺激指数与松醇相比差异为46.7%。
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