Monge Jodra V, Olalla García M T, Sanz Cuesta M T, Gil Recamal A, Pollán Santamaría M A, Pla Mestre R
Servicio de Medicina Preventiva, Hospital Ramón y Cajal, Madrid.
Rev Clin Esp. 1990 May;186(9):423-9.
The aim of the present work was to study hospital infection tendencies and to analyze the variations that have occurred in the accumulated incidence, the localization and the responsible microorganisms in a medical ICU of the Hospital Ramón y Cajal, Madrid during a 5 years period. Nosocomial infections appear with a statistically significant decreasing tendency: the simple regression curve, estimated from the monthly accumulated incidence, presents a slope = -0.16 (p less than 0.05); the adjustment made with the annual accumulated incidence values shows a slope = -2.15 (p less than 0.001). The most frequent localization of hospital infections were: lower respiratory tract, urine, and blood. These infections show in general a decreasing tendency existing a statistical difference in respiratory = -1.5 (p less than 0.001) and urinary = -1.48 (p less than 0.001) infections. The microorganisms most frequently isolated in these patients were P. aeruginosa, S. marcescens and E. coli.
本研究的目的是探讨医院感染趋势，并分析马德里拉蒙·卡哈尔医院重症监护病房在5年期间累积发病率、感染部位及相关微生物的变化情况。医院感染呈现出具有统计学意义的下降趋势：根据每月累积发病率估算的简单回归曲线斜率为-0.16（p<0.05）；对年度累积发病率值进行拟合后斜率为-2.15（p<0.001）。医院感染最常见的部位是：下呼吸道、尿液和血液。总体而言，这些感染呈下降趋势，其中呼吸道感染（斜率=-1.5，p<0.001）和泌尿系统感染（斜率=-1.48，p<0.001）存在统计学差异。这些患者中最常分离出的微生物是铜绿假单胞菌、黏质沙雷氏菌和大肠杆菌。
