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[腹腔镜与内镜对胆总管结石的初始治疗:一项回顾性病例对照研究]

[Laparoscopic versus endoscopic primary management of choledocholithiasis. A retrospective case-control study].

作者信息

Sgourakis G, Lanitis S, Karaliotas Ch, Gockel I, Kaths M, Karaliotas C

机构信息

2nd Surgical Department and Surgical Oncology Unit of Korgialenio - Benakio, Red Cross Hospital Athens, Athens, Greece.

出版信息

Chirurg. 2012 Oct;83(10):897-903. doi: 10.1007/s00104-012-2279-9.

Abstract

BACKGROUND

The aim was to present the long-term results of one-stage laparoscopic procedure for the management of common bile duct (CBD) lithiasis in comparison with the primary endoscopic approach via ERCP.

PATIENTS AND METHODS

A retrospective case-control study was performed to determine the outcome of patients treated for CBD lithiasis (04/1997 - 11/2011). Data of patients with choledocholithiasis undergoing the two treatment modalities - laparoscopic common bile duct exploration plus laparoscopic cholecystectomy (LCBDE + LC, group A, n = 101) versus endoscopic retrograde cholangiopancreatography/sphincterotomy and laparoscopic cholecystectomy (ERCP/S + LC, group B, n = 116) were matched according to their clinical characteristics. Patients of group A underwent either laparoscopic choledochotomy or transcystic exploration. The policy was to convert to open choledochotomy only after the sequential application of the two treatment modalities (laparoscopic/endoscopic procedure) had failed.

RESULTS

No significant difference in morbidity was found between the groups (group A 8% versus group B 11.2%). Conversion to another procedure was mandatory in 12 out of 101 and 17 out of 116 patients of groups A and B, respectively. The mean follow-up period was 7.8 years (range 1-12 years). Effective laparoscopic treatment of CBD stones (cholecystectomy and CBD clearance) was possible in 89 of the 101 patients in group A (88.1%) compared with 99 of the 116 patients in group B (85.4%) after the endoscopic approach.

CONCLUSIONS

This study showes that both - primary endoscopy and one-stage laparoscopic management of CBD lithiasis - are highly effective and safe with comparable results.

摘要

背景

本研究旨在比较一期腹腔镜手术与经内镜逆行胰胆管造影术(ERCP)的主要内镜治疗方法,用于治疗胆总管结石的长期疗效。

患者与方法

进行一项回顾性病例对照研究,以确定接受胆总管结石治疗患者(1997年4月至2011年11月)的治疗结果。对接受两种治疗方式的胆总管结石患者的数据进行匹配,即腹腔镜胆总管探查联合腹腔镜胆囊切除术(LCBDE + LC,A组,n = 101)与内镜逆行胰胆管造影术/括约肌切开术联合腹腔镜胆囊切除术(ERCP/S + LC,B组,n = 116)。A组患者接受腹腔镜胆总管切开术或经胆囊管探查。仅在两种治疗方式(腹腔镜/内镜手术)连续应用失败后才转为开腹胆总管切开术。

结果

两组之间的发病率无显著差异(A组为8%,B组为11.2%)。A组101例患者中有12例、B组116例患者中有17例分别必须转为其他手术。平均随访期为7.8年(范围1 - 12年)。内镜治疗后,A组101例患者中有89例(88.1%)、B组116例患者中有99例(85.4%)成功进行了腹腔镜治疗胆总管结石(胆囊切除术和胆总管结石清除)。

结论

本研究表明,胆总管结石的主要内镜治疗和一期腹腔镜治疗均高效且安全,结果相当。

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