Paroli E, Franco E
Dipartimento di Sanità pubblica, Cattedra di Igiene, II Università, Tor Vergata, Roma.
Recenti Prog Med. 1990 Jul-Aug;81(7-8):539-48.
C. trachomatis, the causative agent of hyperendemic trachoma and lymphogranuloma venereum, is also responsible of sexually transmitted infections. It is now recognized that genital chlamydial infections are the major cause of sexually transmitted diseases in Western industrialized countries, surpassing the importance of gonococcal infections. C. trachomatis, obligate intracellular parasite, enters the epithelial cells of genital mucosae and can reach, luminally, other organs of both female and male genital tract originating different clinical pictures. Vertical transmission of the microorganism from the infected mother to the newborn is of great importance. The infection takes place during delivery and can lead to disease in the newborn such as inclusion conjunctivitis and interstitial pneumonia. The present review deals mainly with clinical features and the most frequent complications of chlamydial infections. The identification of subjects at risk and the improvement of diagnostic techniques is of utmost importance since a prompt antibiotic treatment can eradicate the microorganism at least in uncomplicated infections, preventing the sequelae of the disease.
沙眼衣原体是地方性沙眼和性病性淋巴肉芽肿的病原体,也可导致性传播感染。目前人们认识到,在西方工业化国家,生殖器衣原体感染是性传播疾病的主要原因,其重要性超过了淋球菌感染。沙眼衣原体是专性细胞内寄生虫,可进入生殖器黏膜的上皮细胞,并可经腔道到达女性和男性生殖道的其他器官,引发不同的临床表现。微生物从受感染母亲垂直传播给新生儿极为重要。感染发生在分娩期间,可导致新生儿疾病,如包涵体结膜炎和间质性肺炎。本综述主要探讨衣原体感染的临床特征和最常见的并发症。识别高危人群并改进诊断技术至关重要,因为及时的抗生素治疗至少在无并发症感染中可根除微生物,预防疾病后遗症。