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准分子激光原位角膜磨镶术后上皮松解的发生率及处理

Incidence and management of epithelial loosening after LASIK.

作者信息

Oruçoğlu Faik, Kenduşim Mahir, Ayoglu Buket, Toksu Berrin, Goker Sinan

机构信息

Istanbul Surgery Hospital, POB 34365, Istanbul, Turkey.

出版信息

Int Ophthalmol. 2012 Jun;32(3):225-8. doi: 10.1007/s10792-012-9557-x. Epub 2012 Apr 5.

Abstract

To determine the incidence of recurrent epithelial loosening (REL) following laser in situ keratomileusis (LASIK) and evaluate the efficacy of anterior stromal micropuncture (ASP) and the application of bandage contact lenses (BCLs) in the management of REL after LASIK. A retrospective study including all individuals who underwent LASIK with a microkeratome between January 2006 and January 2007. Medical records were reviewed to identify patients who were diagnosed as having epithelial loosening with or without epithelial defects. Data were collected on 5,566 eyes that underwent LASIK with a microkeratome. Eight eyes (0.14 % or one in 696 eyes) of seven patients had REL with or without epithelial defects. Frequent lubrication, BCL application, and ASP were needed for four eyes (50 %) in the management of REL, respectively. All patients remained free of symptoms after completion of ASP. REL following LASIK is uncommon. Follow-up of patients showed that BCL application and ASP were effective in the management of REL following LASIK.

摘要

确定准分子原位角膜磨镶术(LASIK)后复发性上皮松解(REL)的发生率,并评估前基质微穿刺(ASP)和绷带式隐形眼镜(BCL)在LASIK术后REL治疗中的疗效。一项回顾性研究,纳入了2006年1月至2007年1月期间所有接受微型角膜刀LASIK手术的患者。查阅病历以确定被诊断为有或无上皮缺损的上皮松解患者。收集了5566只接受微型角膜刀LASIK手术眼睛的数据。7例患者的8只眼(0.14%,即696只眼中有1只)出现了有或无上皮缺损的REL。在REL治疗中,分别有4只眼(50%)需要频繁润滑、使用BCL和进行ASP。所有患者在完成ASP后均无症状。LASIK术后的REL并不常见。对患者的随访表明,使用BCL和ASP对LASIK术后的REL治疗有效。

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