Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida 33136, USA.
J Cataract Refract Surg. 2013 Aug;39(8):1241-7. doi: 10.1016/j.jcrs.2013.03.018. Epub 2013 May 24.
To study the utility of creating an additional side cut within the old laser in situ keratomileusis (LASIK) flap using a femtosecond laser to reduce the incidence of epithelial ingrowth in patients having retreatments for residual refractive errors after LASIK.
Bascom Palmer Eye Institute, Miller School of Medicine, Miami, Florida, USA.
Comparative case series.
On a chart review of all cases that had retreatment between January 2004 and April 2011, eyes in which an additional side cut with the femtosecond laser within the old LASIK flap margin was created were classified as Group 1. All eyes having retreatment using traditional flap-relifting techniques between January 2008 and April 2011 were classified as Group 2.
Twenty-four eyes of 18 patients had femtosecond laser-assisted retreatment with side cut only (Group 1), while 103 eyes of 80 patients had a flap-lift LASIK enhancement (Group 2). Twenty-seven cases of epithelial ingrowth were identified in the 2 groups, 4 cases (17%) in the side-cut group and 23 cases (22%) in the flap-lift group. There was a statistically significant difference between the 2 groups in the incidence of epithelial ingrowth in patients in which the microkeratome was used as the initial method of flap creation (P<.05).
Femtosecond laser-assisted side-cut LASIK resulted in a statistically significant lower incidence of epithelial ingrowth after stratification because of the higher risk for epithelial ingrowth in patients who had primary LASIK with microkeratome flaps.
研究使用飞秒激光在旧的 LASIK 瓣内创建额外侧切口以减少 LASIK 后残余屈光不正患者进行翻修时上皮内生长的发生率。
美国佛罗里达州迈阿密市巴斯康帕尔默眼科研究所,米勒医学院。
对比病例系列。
对 2004 年 1 月至 2011 年 4 月期间所有进行翻修的病例进行图表回顾,将在旧 LASIK 瓣边缘使用飞秒激光创建额外侧切口的病例归入第 1 组。将 2008 年 1 月至 2011 年 4 月期间使用传统瓣掀起技术进行翻修的所有病例归入第 2 组。
18 例患者的 24 只眼仅行飞秒激光辅助侧切口翻修(第 1 组),80 例患者的 103 只眼行瓣掀起 LASIK 增强术(第 2 组)。在这 2 组中,共发现 27 例上皮内生长,侧切口组 4 例(17%),瓣掀起组 23 例(22%)。在使用微型角膜刀作为初始瓣制作方法的患者中,2 组间上皮内生长的发生率存在统计学差异(P<.05)。
在分层后,飞秒激光辅助侧切口 LASIK 导致上皮内生长的发生率显著降低,这是由于使用微型角膜刀制作的原发性 LASIK 患者发生上皮内生长的风险较高。