Coppi G
Centro Ricerche, Poli Industria Chimica SpA MI.
Acta Otorhinolaryngol Ital. 1990;10 Suppl 28:35-46.
Tiaprofenic acid is a new generation anti-inflammatory drug synthesized to be a valid alternative to both cortisone preparations and other NSADs since it is less toxic yet equally effective. Its anti-inflammatory, analgesic, antipyretic activity is due to a particular interference mechanism active in the early phases of the inflammatory process (PG synthesis inhibition, stabilization of lysosomal membranes). Thanks to its good trophism toward tissues in the otolaryngological area and its tolerability this drug would appear particularly suited for the treatment of inflammatory E.N.T. pathologies.
噻洛芬酸是一种新一代抗炎药，因其毒性较小但疗效相当，所以被合成作为可的松制剂和其他非甾体抗炎药的有效替代品。其抗炎、镇痛、解热活性归因于在炎症过程早期起作用的一种特殊干扰机制（抑制前列腺素合成、稳定溶酶体膜）。由于其对耳鼻喉科组织具有良好的亲和性及其耐受性，这种药物似乎特别适合治疗耳鼻喉科炎症性疾病。
