Catalano G B, Serra A, Salami A, Tinelli E
Clinica Otorinolaringoiatrica dell'Università di Catania.
Acta Otorhinolaryngol Ital. 1990;10 Suppl 28:63-72.
Mucociliary activity is a fundamental aspect of the clearance function of the respiratory tract; mucociliary transport time being the easiest parameter to record in regard to the overall, more complex function of nasal clearance. A double blind, multicenter randomized study was carried out on 40 rhinopathy patients divided into two groups and treated with tiaprofenic acid 300 mg or a placebo twice a day for seven consecutive days. Before and after treatment the following were recorded: subjective and objective nasal MCT time, using an original composition of vegetable charcoal powder and saccharin powder at 3%; nasal obstruction. The authors conclude that the treatment of rhinitis with tiaprofenic acid improved not only the clinical symptomatology but also the mucociliary transport time and rhinomanometric examination.
黏液纤毛活动是呼吸道清除功能的一个基本方面；黏液纤毛传输时间是记录鼻腔清除这一整体且更为复杂功能时最容易测量的参数。一项双盲、多中心随机研究对40名鼻病患者进行，这些患者被分为两组，连续7天每天两次服用300毫克噻洛芬酸或安慰剂。治疗前后记录了以下指标：使用3%的植物炭粉和糖精粉的原始组合物测量主观和客观鼻腔MCT时间；鼻阻塞情况。作者得出结论，噻洛芬酸治疗鼻炎不仅改善了临床症状，还改善了黏液纤毛传输时间和鼻阻力测量检查结果。
