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噻洛芬酸(“苏尔加姆”)与阿司匹林在控制损伤后疼痛方面的比较试验。

A comparative trial of tiaprofenic acid ('Surgam') versus aspirin in the control of pain following injury.

作者信息

Cutting C J, Thornton E J

出版信息

Pharmatherapeutica. 1981;2(8):509-12.

PMID:7019930
Abstract

A double-blind, non-crossover, randomized trial was carried out in 50 patients suffering from pain following trauma to compare the therapeutic effectiveness and tolerance of 200 mg tiaprofenic acid and 600 mg aspirin given 3-times daily for 7 days. Both drugs were found to be equally effective in relieving pain but side-effects were significantly fewer in the tiaprofenic acid-treated group.

摘要

对50名创伤后疼痛患者进行了一项双盲、非交叉、随机试验,比较每日3次、连续7天服用200毫克噻洛芬酸和600毫克阿司匹林的治疗效果和耐受性。结果发现,两种药物在缓解疼痛方面同样有效,但噻洛芬酸治疗组的副作用明显较少。

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引用本文的文献

1
Single dose oral tiaprofenic acid for acute postoperative pain in adults.单剂量口服噻洛芬酸用于成人急性术后疼痛
Cochrane Database Syst Rev. 2009 Oct 7;2009(4):CD007542. doi: 10.1002/14651858.CD007542.pub2.
2
Tiaprofenic acid. A review of its pharmacological properties and therapeutic efficacy in rheumatic diseases and pain states.噻洛芬酸。对其在风湿性疾病和疼痛状态下的药理特性及治疗效果的综述。
Drugs. 1985 Mar;29(3):208-35. doi: 10.2165/00003495-198529030-00002.