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经皮后根球囊压迫术治疗三叉神经痛:关键技术细节和结果的回顾。

Percutaneous retrogasserian balloon compression for trigeminal neuralgia: review of critical technical details and outcomes.

机构信息

Department of Neurosurgery, Umeå University Hospital, Umeå, Sweden.

出版信息

World Neurosurg. 2013 Feb;79(2):359-68. doi: 10.1016/j.wneu.2012.03.014. Epub 2012 Apr 2.

Abstract

OBJECTIVE

To describe percutaneous balloon compression (PBC) of the trigeminal rootlets as treatment for trigeminal neuralgia (TN), including history, operative techniques, outcomes, side effects, and some recent findings increasing the likelihood of a positive outcome.

METHODS

PBC is indicated in patients with TN in whom microvascular decompression is considered less suitable. The procedure is simplified by the use of biplanar fluoroscopy, although it is usually carried out with C-arm fluoroscopy to facilitate the introduction of the needle and the visualization of the inflated catheter. In the right position, a clearly defined pear shape usually appears after injection of 0.5-0.7 mL of contrast material. The balloon is kept inflated for 1.5-3 minutes. It is crucial to obtain a pear shape because this probably is the most significant factor for obtaining good, long-lasting pain relief.

RESULTS

An analysis of 100 consecutive PBC procedures showed an initial success rate of 90% and a median pain-free time without medication of 28 months. Subdividing these patients into primary TN (n = 77) and TN secondary to multiple sclerosis (n = 23), the median pain-free times were 33 months and 24 months (P = 0.2), indicating that the outcome may depend on the preoperative conditions.

CONCLUSIONS

Complications and side effects include cardiovascular stress during the procedure, local hemorrhages in the cheek, postoperative sensory disturbance, masseter weakness, infections, and transitory diplopia after surgery. Measures to minimize side effects are proposed. With meticulous technique, PBC is a straightforward, effective, and fast procedure that compares well with other percutaneous therapies for TN.

摘要

目的

描述经皮神经根球囊压迫术(PBC)作为治疗三叉神经痛(TN)的方法,包括其历史、手术技术、结果、副作用以及一些增加阳性结果可能性的最新发现。

方法

对于微血管减压术不太适合的 TN 患者,可采用 PBC。虽然通常使用 C 形臂荧光透视术进行该手术,但使用双平面荧光透视术可简化手术过程,便于针的引入和充气导管的可视化。在正确的位置,注射 0.5-0.7ml 造影剂后通常会出现清晰的梨形。球囊充气 1.5-3 分钟。获得梨形非常重要,因为这可能是获得良好、持久止痛效果的最重要因素。

结果

对 100 例连续 PBC 手术进行分析,初始成功率为 90%,中位数无药物止痛时间为 28 个月。将这些患者分为原发性 TN(n=77)和多发性硬化症继发 TN(n=23),中位无疼痛时间分别为 33 个月和 24 个月(P=0.2),表明结果可能取决于术前情况。

结论

并发症和副作用包括手术过程中的心血管应激、脸颊局部出血、术后感觉障碍、咬肌无力、感染以及术后短暂性复视。提出了减少副作用的措施。通过精细的技术,PBC 是一种简单、有效、快速的手术,与其他 TN 的经皮治疗方法相比效果相当。

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