Lima Pessôa Bruno, Hauwanga Wilhelmina N, Thomas Anusha, Valentim Gabriella, McBenedict Billy
Neurosurgery, Fluminense Federal University, Niterói, BRA.
Family Medicine, Faculty of Medicine, Federal University of the State of Rio de Janeiro, Rio de Janeiro, BRA.
Cureus. 2024 Apr 11;16(4):e58025. doi: 10.7759/cureus.58025. eCollection 2024 Apr.
Neuropathic pain is a challenging condition. Despite the immense progress made in the pathophysiology and treatment of such conditions, so much work still has to be done. New frontiers previously unexplored are now objects of study with exciting results, mainly regarding neuromodulation and optogenetics. This review explores the already known pathophysiology and the clinical and surgical treatment in the light of evidence-based medicine. Additionally, new concepts and insights are discussed, presenting the hope for the development of new paradigms in the treatment of neuropathic pain.
神经性疼痛是一种具有挑战性的病症。尽管在这类病症的病理生理学和治疗方面取得了巨大进展，但仍有许多工作要做。以前未被探索的新领域现在成为了研究对象，并取得了令人兴奋的成果，主要涉及神经调节和光遗传学。本综述根据循证医学探讨了已知的病理生理学以及临床和外科治疗方法。此外，还讨论了新的概念和见解，为神经性疼痛治疗新范式的发展带来了希望。
