Bhatt Chirag, Bandyopadhyay Samir Kumar, Chatterjee P K, Paul R C, Bagchi S C, Chatterjee Arkendu
Department, Susrut Eye Foundation and Research Centre, Kolkata 700106.
J Indian Med Assoc. 2011 Oct;109(10):759-61.
Choroidal haemangioma is a benign tumour with visual acuity diminution due to subretinal fluid accumulation. There are many modalities of treatment of this visually disabling syndrome, some of them being argon laser photocoagulation, cryotherapy, external beam irradiation, proton beam radiotherapy, episcleral plaque radiotherapy and transpupillary thermotherapy. Another new modality of treatment with remarkable success rate is photodynamic therapy. In this modality a photosensitiser is injected intravenously followed by irradiation of a specific wave length for a specified time period. The photosensitiser concentrates within the vascular channels and after irradiation these channels are irreversibly obliterated. A 62 years old female patient of choroidal haemangioma, who presented in eye outpatient department was treated with the standard protocol used for photodynamic therapy. On follow-up of this patient it was found that there was improvement in the visual acuity from 6/12 in the left eye (affected eye) to 6/9. Not only was there an improvement in the visual acuity but there was anatomical improvement too as was evident by regressed cystoid macular oedema and circumscribed choroidal haemangioma. After six months of follow-up there was no leakage of dye with digital fluorescein angiography and indocyanine green.
脉络膜血管瘤是一种良性肿瘤，因视网膜下液体积聚导致视力下降。对于这种导致视力丧失的综合征有多种治疗方式，其中包括氩激光光凝、冷冻疗法、外照射放疗、质子束放疗、巩膜外敷贴放疗和经瞳孔温热疗法。另一种成功率显著的新治疗方式是光动力疗法。在这种治疗方式中，先静脉注射一种光敏剂，然后在特定时间段内用特定波长进行照射。光敏剂在血管通道内聚集，照射后这些通道会被不可逆地闭塞。一名62岁的脉络膜血管瘤女性患者在眼科门诊就诊，接受了光动力疗法的标准方案治疗。对该患者进行随访时发现，左眼（患眼）视力从6/12提高到了6/9。不仅视力有所改善，而且从消退的黄斑囊样水肿和局限性脉络膜血管瘤可以明显看出也有解剖学上的改善。随访6个月后，数字荧光素血管造影和吲哚菁绿检查均未发现染料渗漏。
